Evidence map›Paper›PMID 12618368›Full record

ArticleGenome research2003

Genome duplication, a trait shared by 22000 species of ray-finned fish.

John S Taylor, Ingo Braasch, Tancred Frickey, Axel Meyer, Yves Van de Peer

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 369 papers.

0numbers the graph read from it
0cells of the map it votes in
369citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

369 citing papers in PubMed, 889 citations in OpenAlex.

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  4. Ecological opportunity and the onset of polyploid niche expansion waves.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  11. Evolution of Duplicated Hox Gene Clusters in Land Snails and Slugs.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025
    Article
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  15. Review
  16. Natterin bridges IFN-φ1 and non-canonical inflammasome pathways viaFrontiers in cellular and infection microbiology · 2025
    Article
  17. Article
  18. Review
  19. Review
  20. Article

309 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

John S TaylorDepartment of Biology, University of Konstanz, D-78457, Konstanz, Germany.
Ingo Braasch
Tancred Frickey
Axel Meyer
Yves Van de Peer
University of Konstanz · DEUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through phylogeny reconstruction we identified 49 genes with a single copy in man, mouse, and chicken, one or two copies in the tetraploid frog Xenopus laevis, and two copies in zebrafish (Danio rerio). For 22 of these genes, both zebrafish duplicates had orthologs in the pufferfish (Takifugu rubripes). For another 20 of these genes, we found only one pufferfish ortholog but in each case it was more closely related to one of the zebrafish duplicates than to the other. Forty-three pairs of duplicated genes map to 24 of the 25 zebrafish linkage groups but they are not randomly distributed; we identified 10 duplicated regions of the zebrafish genome that each contain between two and five sets of paralogous genes. These phylogeny and synteny data suggest that the common ancestor of zebrafish and pufferfish, a fish that gave rise to approximately 22000 species, experienced a large-scale gene or complete genome duplication event and that the pufferfish has lost many duplicates that the zebrafish has retained.

Indexed as

Gene DuplicationGenomeAnimalsChromosome MappingEvolution, MolecularGenesGenome, HumanHumansMultifactorial InheritancePhenotypePhylogenySyntenyTakifuguZebrafish

Identifiers

PMID12618368
PMCPMC430266
OpenAlexW2162210817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.