Trial reportIEEE transactions on bio-medical engineering2003
Analysis of raw microneurographic recordings based on wavelet de-noising technique and classification algorithm: wavelet analysis in microneurography.
Trial report in IEEE transactions on bio-medical engineering, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 139 citations in OpenAlex.
- Hypertension in Obese Black Women is Not Caused by Increased Sympathetic Vascular Tone.Journal of the American Heart Association · 2017Trial
- Decoding of grasping information from neural signals recorded using peripheral intrafascicular interfaces.Journal of neuroengineering and rehabilitation · 2011Trial
- Hyperadrenergic postural tachycardia syndrome associated with augmented neurovascular transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Addressing transconductance-bandwidth trade-off by three-dimensional electrolyte-surrounded organic electrochemical transistors.Science advances · 2025Article
- Diastolic Blood Pressure Rise During Valsalva as a Surrogate for Sympathetic Activation to Identify Functional Hyperadrenergic Postural Tachycardia Syndrome.Research square · 2025Article
- Spike detection of human sympathetic nerve activity using wavelet transformation and Valsalva maneuver denoising.Journal of neuroscience methods · 2025Article
- Effect of Anesthesia and Diurnal Variation on Chronic Vagus Nerve Activity in Rats.Journal of neuroscience research · 2025Article
- Hyperadrenergic Postural Tachycardia Syndrome: Clinical Biomarkers and Response to Guanfacine.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Advancements in the neurocirculatory reflex response to hypoxia.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Review
- A comparison of wavelet-based action potential detection from the NeuroAmp and the Iowa Bioengineering Nerve Traffic Analysis system.Journal of neurophysiology · 2024Article
- Flexible circumferential bioelectronics to enable 360-degree recording and stimulation of the spinal cord.Science advances · 2024Article
- A century of exercise physiology: key concepts in neural control of the circulation.European journal of applied physiology · 2024Review
- An Artifact-Resistant Feature SKNAER for Quantifying the Burst of Skin Sympathetic Nerve Activity Signal.Biosensors · 2022Article
- Closed-Loop Vagus Nerve Stimulation for the Treatment of Cardiovascular Diseases: State of the Art and Future Directions.Frontiers in cardiovascular medicine · 2022Review
- The significance of neural inter-frequency power correlations.Scientific reports · 2021Article
- Recording and quantifying sympathetic outflow to muscle and skin in humans: methods, caveats and challenges.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Review
- Observational
- Asynchronous action potential discharge in human muscle sympathetic nerve activity.American journal of physiology. Heart and circulatory physiology · 2019Article
- Vagal and Sympathetic Function in Neuropathic Postural Tachycardia Syndrome.Hypertension (Dallas, Tex. : 1979) · 2019Article
- Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses.Biomedical engineering online · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
We propose a new technique for analyzing the raw neurogram which enables the study of the discharge behavior of individual and group neurons. It utilizes an ideal bandpass filter, a modified wavelet de-noising procedure, an action potential detector, and a waveform classifier. We validated our approach with both simulated data generated from muscle sympathetic neurograms sampled at high rates in five healthy subjects and data recorded from seven healthy subjects during lower body negative pressure suction. The modified wavelet method was superior to the classical discriminator method and the regular wavelet de-noising procedure when applied to simulated neuronal signals. The detected spike rate and spike amplitude rate of the action potentials correlated strongly with number of bursts detected in the integrated neurogram (r = 0.79 and 0.89, respectively, p < 0.001). Eight major action potential waveform classes were found to describe more than 81% of all detected action potentials in all subjects. One class had characteristics similar in shape and in average discharge frequency (27.4 +/- 5.1 spikes/min during resting supine position) to those of reported single vasoconstrictor units. The newly proposed technique allows a precise estimate of sympathetic nerve activity and characterization of individual action potentials in multiunit records.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.