ArticleEnvironmental health perspectives2003
Histopathologic and histochemical biomarker responses of Baltic clam, Macoma balthica, to contaminated Sydney Harbour sediment, Nova Scotia, Canada.
Article in Environmental health perspectives, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 52 citations in OpenAlex.
- Monitoring water quality in Sydney Harbour using blue mussels during remediation of the Sydney Tar Ponds, Nova Scotia, Canada.Environmental monitoring and assessment · 2014Article
- Monitoring effects of remediation on natural sediment recovery in Sydney Harbour, Nova Scotia.Environmental monitoring and assessment · 2013Article
- The orientation of water quality variation from the metropolis river-Huangpu River, Shanghai.Environmental monitoring and assessment · 2007Article
- Lead, arsenic, and polycyclic aromatic hydrocarbons in soil and house dust in the communities surrounding the Sydney, Nova Scotia, tar ponds.Environmental health perspectives · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sediments in Sydney Harbour, Nova Scotia, are highly contaminated by polynuclear aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and heavy metals. Histopathologic and histochemical evaluations were made on the Baltic clam, Macoma balthica, exposed to 11 Sydney Harbour sediment samples. Histologic lesions in digestive gland (tubular dilation or atrophy, macrophage aggregates, tubular cell necrosis, and tissue inflammation) and gonads (macrophage aggregates, supporting cell, germ cell, and ovarian cell necroses) were frequently detected in clams exposed to the most contaminated sediments from the harbor. Clams exposed to these contaminated sediments also had the highest acid phosphatase activity. The average scores of tubular dilation or atrophy, ovarian cell necrosis, and the sums of mean digestive gland lesions correlated significantly with sediment PCBs, and the activities of acid phosphatase correlated significantly with sediment heavy metals, PAHs, and PCBs. Among the lesions, digestive gland tubular dilation or atrophy, tubular cell, germ cell, and ovarian cell necroses, and the activity of acid phosphatase are the best sublethal effect indicators in Macoma exposed to Sydney Harbour sediments. Key words: biomarkers, chronic biologic effects, clams, histology, histochemistry, Macoma balthica, marine sediment, polynuclear aromatic hydrocarbons, polychlorinated biphenyls.
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