Endothelin-1: a multifunctional molecule in cancer.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

64 citing papers in PubMed, 182 citations in OpenAlex.

1. Phase 1/2 study of atrasentan combined with pegylated liposomal doxorubicin in platinum-resistant recurrent ovarian cancer.Neoplasia (New York, N.Y.) · 2010
   Trial
2. Expression of endothelin-A-receptor predicts unfavourable response to neoadjuvant chemotherapy in locally advanced breast cancer.British journal of cancer · 2004
   Trial
3. 1,3,4-Oxadiazole-sulfonamide hybrids: recent advances in biological activities, structure-activity relationships, and therapeutic applications.RSC advances · 2026
   Review
4. From sympathetic overdrive phenotype to malignant transformation: 3PM-guided protection against health-to-disease transition and disease progression improving individual outcomes in primary and secondary care.The EPMA journal · 2026
   Article
5. LGMNFrontiers in immunology · 2026
   Article
6. Lowering Blood Pressure, Raising Cancer Risk?: Evidence From Randomized Clinical Trials and Genetic Studies.JACC. CardioOncology · 2025
   Article
7. Blood Pressure Lowering and Risk of Cancer: Individual Participant-Level Data Meta-Analysis and Mendelian Randomization Studies.JACC. CardioOncology · 2025
   Article
8. Identification of ECE2 signaling in promoting non-small lung cancer progression through ET1/YAP1/MAGEA3 axis.Scientific reports · 2025
   Article
9. Psycho-Neuro-EndocrinE-Immunology Therapy of Cancer, Autoimmunity, Geriatric Disorders, Covid-19, and Hypertension.Methods in molecular biology (Clifton, N.J.) · 2025
   Article
10. Endothelin-1 as a Candidate Biomarker of Systemic Sclerosis: A GRADE-Assessed Systematic Review and Meta-Analysis With Meta-Regression.Biomarker insights · 2025
    Article
11. Endothelin-1 and Its Role in Cancer and Potential Therapeutic Opportunities.Biomedicines · 2024
    Review
12. Proteomic analysis of small extracellular vesicles unique to cervical cancer.Translational cancer research · 2023
    Article
13. Repurposing of the Drug Tezosentan for Cancer Therapy.Current issues in molecular biology · 2023
    Review
14. An Overview of Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Canine Tumors: How Far Have We Come?Veterinary sciences · 2022
    Review
15. Plumbagin attenuates Bleomycin-induced lung fibrosis in mice.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
16. Upregulation of Endothelin-1 May Predict Chemotherapy-Induced Cardiotoxicity in Women with Breast Cancer.Journal of clinical medicine · 2022
    Article
17. The Role of Oral Fusobacterium nucleatum in Female Breast Cancer: A Systematic Review and Meta-Analysis.International journal of dentistry · 2022
    Review
18. Genetic Analysis of Functional Rare Germline Variants across Nine Cancer Types from an Electronic Health Record Linked Biobank.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
19. Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-19.Pulmonary pharmacology & therapeutics · 2021
    Review
20. Endothelin-1 induces changes in the expression levels of steroidogenic enzymes and increases androgen receptor and testosterone production in the PC3 prostate cancer cell line.Oncology reports · 2021
    Article

4 more citing papers are in PubMed but not listed here.

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as