ReviewJournal of clinical pathology2003
HPV infections in benign and malignant sinonasal lesions.
Review in Journal of clinical pathology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 164 citations in OpenAlex.
- Human Papilloma Virus Infection and Sinonasal Inverted Papilloma Recurrence: A Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Pooled it
- Impact of human papillomaviruses (HPV) on recurrence rate and malignant progression of sinonasal papillomas.Cancer medicine · 2021Trial
- HPV11 targeting KDM4A regulates the polarization of macrophage MCell communication and signaling : CCS · 2024Article
- Evaluation of high-risk human papillomavirus in sinonasal papillomas and squamous cell carcinomas.Virchows Archiv : an international journal of pathology · 2023Article
- Sinonasal Inverted Papilloma: A Narrative Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Human Papillomavirus-Related Carcinomas of the Sinonasal Tract.Current otorhinolaryngology reports · 2022Article
- The prognostic significance of human papilloma virus in sinonasal squamous cell carcinoma.Laryngoscope investigative otolaryngology · 2020Article
- Identification of Rare and Common HPV Genotypes in Sinonasal Papillomas.Head and neck pathology · 2020Article
- Low prevalence of human papillomavirus infection in sinonasal inverted papilloma and oncocytic papilloma.Virchows Archiv : an international journal of pathology · 2020Article
- Article
- Human Papillomavirus Infection in Head and Neck Squamous Cell Carcinomas: Transcriptional Triggers and Changed Disease Patterns.Frontiers in cellular and infection microbiology · 2020Review
- [An unusual case of condylomata acuminata identified in the nasal cavity of a patient living in Yaoundé, Cameroon: a clinical report and literature review].The Pan African medical journal · 2020Review
- OSPs and ESPs and ISPs, Oh My! An Update on Sinonasal (Schneiderian) Papillomas.Head and neck pathology · 2017Review
- Transcriptionally Active High-Risk Human Papillomavirus is Not a Common Etiologic Agent in the Malignant Transformation of Inverted Schneiderian Papillomas.Head and neck pathology · 2017Article
- Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence.Imaging science in dentistry · 2017Article
- Immunohistochemical Study EMT-Related Proteins in HPV-, and EBV-Negative Patients with Sinonasal Tumours.Pathology oncology research : POR · 2016Article
- Low-Grade Epithelial Proliferations of the Sinonasal Tract.Head and neck pathology · 2016Review
- Immunohistochemical study on ADAM33 in sinonasal inverted papillomas and squamous cell carcinomas of the larynx.Archives of medical science : AMS · 2016Article
- The presence of high-risk human papillomavirus (HPV) E6/E7 mRNA transcripts in a subset of sinonasal carcinomas is evidence of involvement of HPV in its etiopathogenesis.Virchows Archiv : an international journal of pathology · 2015Article
- Inverted Papilloma Originating Primarily from the Nasolacrimal Duct: A Case Report and Review of the Pertinent Literature.Case reports in otolaryngology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review updates the evidence that the human papillomavirus (HPV) is involved in the development of benign and malignant sinonasal lesions. Since the early 1980s, when evidence was provided on the possible involvement of HPV in the aetiology of both benign respiratory papillomas and squamous cell carcinomas, a substantial number of studies have explored this issue. To date, 33.3% of sinonasal papillomas and 21.7% of sinonasal carcinomas analysed have been shown to be positive for HPV. Many elements of the data parallel the observations made in HPV lesions at other mucosal sites, such as malignant transformation and frequent recurrence after radical treatment; the fact that low risk HPV types 6 and 11 are usually confined to benign lesions, whereas the reverse is true for the oncogenic HPV types 16 and 18; and the presence of squamo-columnar junctions and squamous cell metaplasia in the sinonasal system. The discrepancies reported by several studies might result in part from technical reasons, but it is also possible that sinonasal lesions have a heterogeneous aetiology (HPV related and non-related) and/or that some novel (yet unidentified) HPV types exist in these lesions, which are detected by some studies but not by others.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.