ArticleLangenbeck's archives of surgery2003
Does anastomotic leakage affect functional outcome after rectal resection for cancer?
Article in Langenbeck's archives of surgery, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Association between anastomotic leak after rectal resection and bowel dysfunction, a systematic review, meta-analysis and meta-regression.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Pooled it
- Pooled it
- Impact of anastomotic leakage and radiotherapy on long-term quality of life after sphincter-saving rectal resections.Langenbeck's archives of surgery · 2025Article
- The effect of anastomotic leak on postoperative pelvic function and quality of life in rectal cancer patients.Discover oncology · 2022Review
- Tailored treatment of anastomotic leak after rectal cancer surgery according to the presence of a diverting stoma.Annals of surgical treatment and research · 2020Article
- Is my life going to change?-a review of quality of life after rectal resection.Journal of gastrointestinal oncology · 2020Review
- Risk factor for permanent stoma and incontinence quality of life after sphincter-preserving surgery for low rectal cancer without a diverting stoma.Annals of gastroenterological surgery · 2018Article
- The Impact of Anastomotic Leakage on Anal Function Following Intersphincteric Resection.World journal of surgery · 2017Article
- Low anterior resection syndrome: a survey of the members of the American Society of Colon and Rectal Surgeons (ASCRS), the Spanish Association of Surgeons (AEC), and the Spanish Society of Coloproctology (AECP).International journal of colorectal disease · 2016Article
- Predictors of fecal incontinence and related quality of life after a total mesorectal excision with primary anastomosis for patients with rectal cancer.Annals of coloproctology · 2015Article
- Diverting stoma with anterior resection for rectal cancer: does it reduce overall anastomotic leakage and leaks requiring laparotomy?International journal of clinical and experimental medicine · 2015Article
- Does anastomotic leakage impair functional results and quality of life after laparoscopic sphincter-saving total mesorectal excision for rectal cancer? A case-matched study.International journal of colorectal disease · 2014Article
- Outcomes of asymptomatic anastomotic leaks found on routine postoperative water-soluble enema following anterior resection for cancer.World journal of surgery · 2013Article
- Low anterior resection syndrome (LARS): cause and effect and reconstructive considerations.Techniques in coloproctology · 2013Review
- Pelvic organ function and quality of life after anastomotic leakage following rectal cancer surgery.Wiener klinische Wochenschrift · 2011Article
- Quality management in rectal carcinoma: what is feasible?International journal of colorectal disease · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnastomotic leakage is the most threatening early complication in sphincter-preserving rectal cancer surgery. While the oncological consequences have been well examined, only few data exist about the functional outcome. PATIENTS AND
methodsWe investigated continence function in 150 patients after curative sphincter-preserving rectal cancer surgery. Functional results were compared in 22 patients with a clinically relevant anastomotic leakage, confirmed radiologically or endoscopically, and 128 patients with uneventful recovery. Evaluation of continence function was based on the Cleveland Clinic Continence Score and was examined in all patients with anastomotic leakage and in 111 patients without complications 107+/-46 weeks postoperatively. Additionally, 14 patients with anastomotic leakage and 58 patients with uneventful recovery underwent anorectal manometry 26+/-15 weeks postoperatively.
resultsThe continence score in patients after anastomotic leakage did not differ significantly from that in patients without complications. Sphincter function was similar. Maximum tolerable volume and rectal compliance were slightly but not significantly worse after leakage.
conclusionsContinence function remained undisturbed after anastomotic leakage due to rectal resection
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.