ArticleAntimicrobial agents and chemotherapy2003
In vitro effects of ciprofloxacin and roxithromycin on apoptosis of jurkat T lymphocytes.
Article in Antimicrobial agents and chemotherapy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- A prospective randomly controlled clinical trial on azithromycin therapy for induction treatment of children with nephrotic syndrome.European journal of pediatrics · 2014Trial
- Blood Compatibility-An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application.International journal of molecular sciences · 2019Article
- Ciprofloxacin Enhances TRAIL-Induced Apoptosis in Lung Cancer Cells by Upregulating the Expression and Protein Stability of Death Receptors through CHOP Expression.International journal of molecular sciences · 2018Article
- Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.Scientific reports · 2017Article
- Antibacterial Activity of Ciprofloxacin-Encapsulated Cockle Shells Calcium Carbonate (Aragonite) Nanoparticles and Its Biocompatability in Macrophage J774A.1.International journal of molecular sciences · 2016Article
- Article
- Genotoxic effect of ciprofloxacin during photolytic decomposition monitored by the in vitro micronucleus test (MNvit) in HepG2 cells.Environmental science and pollution research international · 2012Article
- Gatifloxacin induces S and G2-phase cell cycle arrest in pancreatic cancer cells via p21/p27/p53.PloS one · 2012Article
- Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines.PloS one · 2012Article
- The effect of ciprofloxacin on sperm DNA damage, fertility potential and early embryonic development in NMRI mice.Veterinary research forum : an international quarterly journal · 2012Article
- Mechanisms of action and clinical application of macrolides as immunomodulatory medications.Clinical microbiology reviews · 2010Review
- Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation.Cancer biology & therapy · 2008Article
- Calcium signals are affected by ciprofloxacin as a consequence of reduction of mitochondrial DNA content in Jurkat cells.Antimicrobial agents and chemotherapy · 2006Article
- Use of antimicrobials and risk of type 1 diabetes in a population-based mother-child cohort.Diabetologia · 2006Article
- Effect of moxifloxacin on production of proinflammatory cytokines from human peripheral blood mononuclear cells.Antimicrobial agents and chemotherapy · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ciprofloxacin (CPFX) and roxithromycin (RXM) induced apoptosis of activated Jurkat T cells in vitro. CPFX showed concentration-dependent acceleration of apoptosis of activated Jurkat T cells by enhancing the expression of FasL and activities of caspase-3 and -8. RXM accelerated cell death, enhanced expression of FasL and caspase-3 but not caspase-8, and did not show the concentration dependency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.