ArticlePlant molecular biology2003
Characterization of Arabidopsis plastid sigma-like transcription factors SIG1, SIG2 and SIG3.
Article in Plant molecular biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Genome-Wide Identification of Sigma Factors inInternational journal of molecular sciences · 2026Article
- Regreening mechanisms in cucumber: insights from a CsSIG2 mutation affecting chloroplast development.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- High-resolution map of plastid-encoded RNA polymerase binding patterns demonstrates a major role of transcription in chloroplast gene expression.The Plant journal : for cell and molecular biology · 2022Article
- Identification of biological pathway and process regulators using sparse partial least squares and triple-gene mutual interaction.Scientific reports · 2021Article
- A PPR Protein ACM1 Is Involved in Chloroplast Gene Expression and Early Plastid Development inInternational journal of molecular sciences · 2021Article
- A pentatricopeptide repeat protein DUA1 interacts with sigma factor 1 to regulate chloroplast gene expression in Rice.Photosynthesis research · 2021Article
- Plastid Gene Transcription: An Update on Promoters and RNA Polymerases.Methods in molecular biology (Clifton, N.J.) · 2021Article
- HB-PLS: A statistical method for identifying biological process or pathway regulators by integrating Huber loss and Berhu penalty with partial least squares regression.Forestry research · 2021Article
- Transcriptome-wide shift from photosynthesis and energy metabolism upon endogenous fluid protein depletion in young Nepenthes ampullaria pitchers.Scientific reports · 2020Article
- Sigma factor 1 in chloroplast gene transcription and photosynthetic light acclimation.Journal of experimental botany · 2020Article
- Extrachloroplastic PP7L Functions in Chloroplast Development and Abiotic Stress Tolerance.Plant physiology · 2019Article
- Leaf Variegation of Thylakoid Formation1 Is Suppressed by Mutations of Specific σ-Factors in Arabidopsis.Plant physiology · 2015Article
- Phytochrome-dependent coordinate control of distinct aspects of nuclear and plastid gene expression during anterograde signaling and photomorphogenesis.Frontiers in plant science · 2014Article
- AtSIG6 and other members of the sigma gene family jointly but differentially determine plastid target gene expression in Arabidopsis thaliana.Frontiers in plant science · 2014Article
- Phytochrome-induced SIG2 expression contributes to photoregulation of phytochrome signalling and photomorphogenesis in Arabidopsis thaliana.Journal of experimental botany · 2013Article
- Plastid gene expression during chloroplast differentiation and dedifferentiation into non-photosynthetic plastids during seed formation.Plant molecular biology · 2013Article
- Review
- Sigma factor-mediated plastid retrograde signals control nuclear gene expression.The Plant journal : for cell and molecular biology · 2013Article
- Subfunctionalization of sigma factors during the evolution of land plants based on mutant analysis of liverwort (Marchantia polymorpha L.) MpSIG1.Genome biology and evolution · 2013Article
- SIG1, a sigma factor for the chloroplast RNA polymerase, differently associates with multiple DNA regions in the chloroplast chromosomes in vivo.International journal of molecular sciences · 2012Article
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Authors and funding
5 authors.
Funding
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Abstract
The plastid genome is transcribed by nucleus-encoded (NEP) and plastid-encoded (PEP) RNA polymerases. PEP is a prokaryotic-type enzyme whose activity is regulated by sigma-like transcription initiation factors that are nucleus-encoded. cDNAs coding for six different potential a-like factors have been cloned and sequenced recently. However, functional analyses of these factors are still limited. We have used an anti-sense approach in order to study the function of SIG1, SIG2 and SIG3. Only SIG2 anti-sense plants show a visible phenotype characterized by chlorophyll deficiency. Surprisingly, this phenotype is different from the phenotype of SIG2 knockout plants in that the chlorophyll deficiency is limited to cotyledons. In later developmental stages, the SIG2 anti-sense plants can overcome SIG2 mRNA under-expression by adjusting SIG2 protein levels to that of wild-type plants, suggesting that SIG2 expression is also regulated at the post-transcriptional level. The efficient recovery of the wild-type phenotype could also be supported by partial take-over of SIG2 function by one of the six other sigma factors. A good candidate for such substitution of SIG2 function represents SIG3. SIG3 is constitutively expressed during plant development and its specificity in promoter discrimination is less pronounced than that of SIG1 and SIG2. Finally, SIG3 protein is enhanced in SIG2 anti-sense plants when compared to wild-type plants. SIG2 is present as a soluble factor while SIG3 is partly attached to the plastid membranes. We suggest that membrane localization is necessary for efficient SIG3 function. Therefore, SIG3 cannot substitute for SIG2 function in early chloroplast biogenesis, when plastid membranes are not yet made up.
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