ReviewDrugs2003
Diagnosis and treatment of patients with pouchitis.
Review in Drugs, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Active Pouchitis
Fecal Microbiota Transplantation for the Treatment of Chronic Pouchitis
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis.World journal of gastroenterology · 2014Pooled it
- Antibiotics and probiotics in chronic pouchitis: a comparative proteomic approach.World journal of gastroenterology · 2010Trial
- Effects of probiotic on intestinal mucosa of patients with ulcerative colitis.World journal of gastroenterology · 2004Trial
- Efficiency of Diagnostic Testing forAntibiotics (Basel, Switzerland) · 2021Review
- Medical treatment of pouchitis: a guide for the clinician.Therapeutic advances in gastroenterology · 2021Review
- The relationship between preoperative T helper cytokines in the ileal mucosa and the pathogenesis of pouchitis.BMC gastroenterology · 2020Article
- Ileal-anal pouches: A review of its history, indications, and complications.World journal of gastroenterology · 2019Review
- Association between serum tumor necrosis factor-alpha level and the efficacy of infliximab for refractory pouchitis after restorative proctocolectomy in patients with ulcerative colitis.Journal of the anus, rectum and colon · 2017Article
- Clinical features and management of pouchitis in Japanese ulcerative colitis patients.Surgery today · 2013Article
- Pouchitis: a practical guide.Frontline gastroenterology · 2013Review
- Chronic use of PPI and H2 antagonists decreases the risk of pouchitis after IPAA for ulcerative colitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Article
- Acute and chronic pouchitis--pathogenesis, diagnosis and treatment.Nature reviews. Gastroenterology & hepatology · 2012Review
- Evaluation of upper and lower gastrointestinal histology in patients with ileal pouches.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2012Article
- Surgical prophylaxis of pouchitis in ulcerative colitis.Digestive diseases and sciences · 2011Review
- Diagnosis and management of postoperative ileal pouch disorders.Clinics in colon and rectal surgery · 2010Article
- The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing.Annals of surgery · 2010Article
- Pouchitis disease activity index (PDAI) does not predict patients with symptoms of pouchitis who will respond to antibiotics.Surgery today · 2009Article
- Diagnosis and treatment of pouchitis.Gastroenterology & hepatology · 2008Article
- Pouchitis.World journal of gastroenterology · 2007Review
- [Ileo pouch-anal anastomosis].Der Internist · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pouchitis is the most common long-term complication of ileal pouch-anal anastomosis in patients with underlying ulcerative colitis. Clinical symptoms of pouchitis are not specific, and they can be caused by other conditions such as rectal cuff inflammation and irritable pouch syndrome. Therefore, to make an accurate diagnosis, endoscopic evaluation together with symptom assessment is necessary. Among five available treat-first and test-first strategies, the initial approach with pouch endoscopy without histology was the most cost-effective strategy for the diagnosis of pouchitis. On the basis of clinical course, pouchitis can be classified into acute, relapsing and chronic forms. Pouchitis can also be classified into three categories based on the response to antibacterial therapy: antibacterial-responsive; antibacterial-dependent; and antibacterial-resistant. Metronidazole and ciprofloxacin are both effective in treating acute pouchitis. Although antibacterial therapy can induce and maintain remission, probiotics such as VSL#3 can also be used as to maintain clinical remission and prevent relapse in patients with relapsing or chronic pouchitis. For patients with chronic pouchitis that is resistant to antibacterials, therapy with anti-inflammatory agents and immunomodulators is often required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.