ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2003
A dynamic dendritic refractory period regulates burst discharge in the electrosensory lobe of weakly electric fish.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 54 citations in OpenAlex.
- Neural Synchrony Gives Rise to Amplitude- and Duration-Invariant Encoding Consistent With Perception of Natural Communication Stimuli.Frontiers in neuroscience · 2020Article
- Data-driven inference for stationary jump-diffusion processes with application to membrane voltage fluctuations in pyramidal neurons.Journal of mathematical neuroscience · 2019Article
- Variable synaptic strengths controls the firing rate distribution in feedforward neural networks.Journal of computational neuroscience · 2018Article
- Burst Firing in the Electrosensory System of Gymnotiform Weakly Electric Fish: Mechanisms and Functional Roles.Frontiers in computational neuroscience · 2016Review
- Activation of parallel fiber feedback by spatially diffuse stimuli reduces signal and noise correlations via independent mechanisms in a cerebellum-like structure.PLoS computational biology · 2015Article
- A neural code for looming and receding motion is distributed over a population of electrosensory ON and OFF contrast cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Learning contrast-invariant cancellation of redundant signals in neural systems.PLoS computational biology · 2013Article
- Peripheral drive in Aα/β-fiber neurons is altered in a rat model of osteoarthritis: changes in following frequency and recovery from inactivation.Journal of pain research · 2013Article
- In vivo conditions influence the coding of stimulus features by bursts of action potentials.Journal of computational neuroscience · 2011Article
- Frequency-tuned cerebellar channels and burst-induced LTD lead to the cancellation of redundant sensory inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Routing the flow of sensory signals using plastic responses to bursts and isolated spikes: experiment and theory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Neural heterogeneities and stimulus properties affect burst coding in vivo.Neuroscience · 2010Article
- SK channels gate information processing in vivo by regulating an intrinsic bursting mechanism seen in vitro.Journal of neurophysiology · 2009Article
- Population coding by electrosensory neurons.Journal of neurophysiology · 2008Article
- Distribution and function of potassium channels in the electrosensory lateral line lobe of weakly electric apteronotid fish.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2006Review
- A C-terminal domain directs Kv3.3 channels to dendrites.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- High-threshold K+ current increases gain by offsetting a frequency-dependent increase in low-threshold K+ current.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- Parallel processing of sensory input by bursts and isolated spikes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Releasing the peri-neuronal net to patch-clamp neurons in adult CNS.Pflugers Archiv : European journal of physiology · 2004Article
- Ionic and neuromodulatory regulation of burst discharge controls frequency tuning.Journal of physiology, ParisReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Na+-dependent spikes initiate in the soma or axon hillock region and actively backpropagate into the dendritic arbor of many central neurons. Inward currents underlying spike discharge are offset by outward K+ currents that repolarize a spike and establish a refractory period to temporarily prevent spike discharge. We show in a sensory neuron that somatic and dendritic K+ channels differentially control burst discharge by regulating the extent to which backpropagating dendritic spikes can re-excite the soma. During repetitive discharge a progressive broadening of dendritic spikes promotes a dynamic increase in dendritic spike refractory period. A leaky integrate-and-fire model shows that spike bursts are terminated when a decreasing somatic interspike interval and an increasing dendritic spike refractory period synergistically act to block backpropagation. The time required for the somatic interspike interval to intersect with dendritic refractory period determines burst frequency, a time that is regulated by somatic and dendritic spike repolarization. Thus, K+ channels involved in spike repolarization can efficiently control the pattern of spike output by establishing a soma-dendritic interaction that invokes dynamic shifts in dendritic spike properties.
Indexed as
Identifiers
12598641PMC6742271W2095656493What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.