ArticleNucleic acids research2003
RNA sequences that work as transcriptional activating regions.
Article in Nucleic acids research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Decoding RNA-protein interactions using high-throughput methods.RNA biology · 2026Review
- Reprogramming cell fate with artificial transcription factors.FEBS letters · 2018Review
- Nucleosome distortion as a possible mechanism of transcription activation domain function.Epigenetics & chromatin · 2016Review
- Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.The Biochemical journal · 2014Review
- Versatile RNA-sensing transcriptional regulators for engineering genetic networks.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Tracking, tuning, and terminating microbial physiology using synthetic riboregulators.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis.American journal of physiology. Endocrinology and metabolism · 2010Article
- An RNA-based transcription activator derived from an inhibitory aptamer.Nucleic acids research · 2010Article
- A three-hybrid screen identifies mRNAs controlled by a regulatory protein.RNA (New York, N.Y.) · 2006Article
- A yeast RNA-hybrid system for the detection of RNA-RNA interactions in vivo.RNA (New York, N.Y.) · 2006Article
- Small-molecule regulators that mimic transcription factors.Biochimica et biophysica actaReview
- Riboactivators: transcription activation by noncoding RNA.Critical reviews in biochemistry and molecular biologyReview
Corrections and comments
- Erratum issuedJarell KA [corrected to Jarrell KA]
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a set of RNA molecules that work as transcriptional activators when tethered to DNA. These RNA activating regions were found amongst a randomized set of molecules bearing variants of a 10 nt loop attached to an RNA stem. The various RNA activating regions all bear an identical five- residue sequence with an interspersed sixth residue. The result shows that although all natural activating regions characterized thus far are peptidic, this function can be served by other kinds of moieties as well.
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Registered trials
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