ArticleInfection and immunity2003
Bacterial [Cu,Zn]-cofactored superoxide dismutase protects opsonized, encapsulated Neisseria meningitidis from phagocytosis by human monocytes/macrophages.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Article
- Antioxidant enzymes activities of Burkholderia spp. strains-oxidative responses to Ni toxicity.Environmental science and pollution research international · 2015Article
- Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus.Journal of bacteriology · 2015Article
- How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines.Journal of immunology research · 2015Review
- Metabolism and virulence in Neisseria meningitidis.Frontiers in cellular and infection microbiology · 2014Review
- Where does Neisseria acquire foreign DNA from: an examination of the source of genomic and pathogenic islands and the evolution of the Neisseria genus.BMC evolutionary biology · 2013Article
- SodA is a major metabolic antioxidant in Brucella abortus 2308 that plays a significant, but limited, role in the virulence of this strain in the mouse model.Microbiology (Reading, England) · 2012Article
- Glutamate utilization promotes meningococcal survival in vivo through avoidance of the neutrophil oxidative burst.Molecular microbiology · 2011Article
- Transcriptome analysis of Neisseria meningitidis in human whole blood and mutagenesis studies identify virulence factors involved in blood survival.PLoS pathogens · 2011Article
- Regulation and activity of a zinc uptake regulator, Zur, in Corynebacterium diphtheriae.Journal of bacteriology · 2009Article
- Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence.The Journal of biological chemistry · 2008Article
- AP endonuclease paralogues with distinct activities in DNA repair and bacterial pathogenesis.The EMBO journal · 2007Article
- Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes.Genome biology · 2007Article
- Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity.Journal of bacteriology · 2006Article
- The Brucella abortus Cu,Zn superoxide dismutase is required for optimal resistance to oxidative killing by murine macrophages and wild-type virulence in experimentally infected mice.Infection and immunity · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Superoxide dismutase cofactored by copper and zinc ([Cu,Zn]-SOD) contributes to the protection of opsonized serogroup B Neisseria meningitidis against phagocytosis by human monocytes/macrophages, with sodC mutant organisms being endocytosed in significantly higher numbers than are wild-type organisms. The influence of [Cu,Zn]-SOD was found to be exerted at the stage of phagocytosis, rather than at earlier (modulating surface association) or later (intracellular killing) stages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.