ArticleInfection and immunity2003
Interleukin-12 regulates chemokine gene expression during the early immune response to Leishmania major.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- The cytokine/chemokine response inHeliyon · 2023Review
- Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor.PLoS neglected tropical diseases · 2021Article
- Early Transcriptional Liver Signatures in Experimental Visceral Leishmaniasis.International journal of molecular sciences · 2021Article
- Pathogen Evasion of Chemokine Response Through Suppression of CXCL10.Frontiers in cellular and infection microbiology · 2019Article
- Chronicity of dermal leishmaniasis caused by Leishmania panamensis is associated with parasite-mediated induction of chemokine gene expression.Infection and immunity · 2014Article
- Immunomodulation in human dendritic cells leads to induction of interferon-gamma production by Leishmania donovani derived KMP-11 antigen via activation of NF-κB in Indian kala-azar patients.BioMed research international · 2014Article
- Chemokines and chemokine receptors expression in the lesions of patients with American cutaneous leishmaniasis.Memorias do Instituto Oswaldo Cruz · 2013Article
- Pathogen-derived oligosaccharides improve innate immune response to intracellular parasite infection.The American journal of pathology · 2011Article
- Role of chemokines in regulation of immunity against leishmaniasis.Experimental parasitology · 2010Review
- Role of natural killer cells in modulating dendritic cell responses to Leishmania amazonensis infection.Infection and immunity · 2008Article
- Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site.The Journal of clinical investigation · 2008Article
- Leishmania-derived murine monocyte chemoattractant protein 1 enhances the recruitment of a restrictive population of CC chemokine receptor 2-positive macrophages.Infection and immunity · 2007Article
- Invariant NKT cells are essential for the regulation of hepatic CXCL10 gene expression during Leishmania donovani infection.Infection and immunity · 2005Article
- Leishmania major modulates chemokine and chemokine receptor expression by dendritic cells and affects their migratory capacity.Infection and immunity · 2005Article
- Chemokine gene expression in toll-like receptor-competent and -deficient mice infected with Leishmania major.Infection and immunity · 2004Article
- Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.Infection and immunity · 2004Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Following infection with Leishmania major, the chemokines XCL1, CXCL10, and CCL2 were preferentially expressed in draining lymph nodes of resistant mice. Neutralization of interleukin 12 (IL-12) or gamma interferon in resistant mice resulted in decreased chemokine expression, while administration of IL-12 to susceptible mice resulted in an increase in the level of chemokine gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.