Evidence map›Paper›PMID 12595379›Full record

ArticleBMJ (Clinical research ed.)2003

Maternal consumption of coffee during pregnancy and stillbirth and infant death in first year of life: prospective study.

Kirsten Wisborg, Ulrik Kesmodel, Bodil Hammer Bech, Morten Hedegaard, Tine Brink Henriksen

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Maternal Caffeine Consumption and Pregnancy Outcomes.Advances in experimental medicine and biology · 2026
    Review
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  7. Article
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  11. Article
  12. Review
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  15. Article
  16. Review
  17. Lifestyle factors and reproductive health: taking control of your fertility.Reproductive biology and endocrinology : RB&E · 2013
    Review
  18. Article
  19. Coffee: advice for our vice?Canadian family physician Medecin de famille canadien · 2013
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Kirsten WisborgPerinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark. kiwi@perinatal.dk
Ulrik Kesmodel
Bodil Hammer Bech
Morten Hedegaard
Tine Brink Henriksen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the association between coffee consumption during pregnancy and the risk of stillbirth and infant death in the first year of life.

designProspective follow up study.

settingAarhus University Hospital, Denmark, 1989-96.

participants18 478 singleton pregnancies in women with valid information about coffee consumption during pregnancy.

main outcome measuresStillbirth (delivery of a dead fetus at > or =28 weeks' gestation) and infant death (death of a liveborn infant during the first year of life).

resultsPregnant women who drank eight or more cups of coffee per day during pregnancy had an increased risk of stillbirth compared with women who did not drink coffee (odds ratio=3.0, 95% confidence interval 1.5 to 5.9). After adjustment for smoking habits and alcohol intake during pregnancy, the relative risk of stillbirth decreased slightly. Adjustment for parity, maternal age, marital status, years of education, occupational status, and body mass index did not substantially change the estimates of association. There was no significant association between coffee consumption and death in the first year of life after adjustment for smoking habits during pregnancy.

conclusionDrinking coffee during pregnancy is associated with an increased risk of stillbirth but not with infant death.

Indexed as

Infant MortalityCoffeeDenmarkFemaleFetal DeathHumansInfantInfant, NewbornOdds RatioPregnancyPrenatal Exposure Delayed EffectsProspective StudiesRisk FactorsCoffee

Identifiers

PMID12595379
PMCPMC149440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.