ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2003
How big is the iceberg of which organellar genes in nuclear genomes are but the tip?
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 211 citations in OpenAlex.
- Comprehensive analysis of the mechanisms conferring resistance to phenamacril in theFrontiers in cellular and infection microbiology · 2025Review
- Dollo Parsimony Overestimates Ancestral Gene Content Reconstructions.Genome biology and evolution · 2024Article
- Old genes in new places: A taxon-rich analysis of interdomain lateral gene transfer events.PLoS genetics · 2022Article
- Horizontal gene transfer provides insights into the deep evolutionary history and biology ofFood and waterborne parasitology · 2022Article
- Integrative modeling of gene and genome evolution roots the archaeal tree of life.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Horizontal gene transfer drives the evolution of Rh50 permeases in prokaryotes.BMC evolutionary biology · 2017Article
- Extensive horizontal gene transfer, duplication, and loss of chlorophyll synthesis genes in the algae.BMC evolutionary biology · 2015Article
- The pan-genome as a shared genomic resource: mutual cheating, cooperation and the black queen hypothesis.Frontiers in microbiology · 2015Article
- HGTector: an automated method facilitating genome-wide discovery of putative horizontal gene transfers.BMC genomics · 2014Article
- Horizontal transfers and gene losses in the phospholipid pathway of bartonella reveal clues about early ecological niches.Genome biology and evolution · 2014Article
- Quartet-based methods to reconstruct phylogenetic networks.BMC systems biology · 2014Article
- The scale and evolutionary significance of horizontal gene transfer in the choanoflagellate Monosiga brevicollis.BMC genomics · 2013Article
- Horizontal gene transfer in eukaryotes: the weak-link model.BioEssays : news and reviews in molecular, cellular and developmental biology · 2013Article
- Quartet-net: a quartet-based method to reconstruct phylogenetic networks.Molecular biology and evolution · 2013Article
- Nuclear localization signals in phage terminal proteins provide a novel gene delivery tool in mammalian cells.Communicative & integrative biology · 2013Article
- Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples.PLoS computational biology · 2013Article
- Functional eukaryotic nuclear localization signals are widespread in terminal proteins of bacteriophages.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- ALF--a simulation framework for genome evolution.Molecular biology and evolution · 2012Article
- Extensive Inter-Domain Lateral Gene Transfer in the Evolution of the Human Commensal Methanosphaera stadtmanae.Frontiers in genetics · 2012Article
- The infinitely many genes model for the distributed genome of bacteria.Genome biology and evolution · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As more and more complete bacterial and archaeal genome sequences become available, the role of lateral gene transfer (LGT) in shaping them becomes more and more clear. Over the long term, it may be the dominant force, affecting most genes in most prokaryotes. We review the history of LGT, suggesting reasons why its prevalence and impact were so long dismissed. We discuss various methods purporting to measure the extent of LGT, and evidence for and against the notion that there is a core of never-exchanged genes shared by all genomes, from which we can deduce the "true" organismal tree. We also consider evidence for, and implications of, LGT between prokaryotes and phagocytic eukaryotes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.