ReviewJournal of anatomy2003
Regulation of myogenic differentiation in the developing limb bud.
Review in Journal of anatomy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- RRM2 promotes the proliferation of chicken myoblasts, inhibits their differentiation and muscle regeneration.Poultry science · 2024Article
- Tissues and Cell Types of Appendage Regeneration: A Detailed Look at the Wound Epidermis and Its Specialized Forms.Frontiers in physiology · 2021Review
- Primary myogenesis in the sand lizard (Lacerta agilis) limb bud.Development genes and evolution · 2019Article
- Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling.Development (Cambridge, England) · 2019Article
- Obestatin Increases the Regenerative Capacity of Human Myoblasts Transplanted Intramuscularly in an Immunodeficient Mouse Model.Molecular therapy : the journal of the American Society of Gene Therapy · 2017Article
- Axial and limb muscle development: dialogue with the neighbourhood.Cellular and molecular life sciences : CMLS · 2016Review
- The making of an octopus arm.EvoDevo · 2015Article
- Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.Genes & development · 2012Article
- Three-dimensional observation of the mouse embryo by micro-computed tomography: Meckel's cartilage, otocyst, and/or muscle of tongue.Odontology · 2012Article
- Slowing down differentiation of engrafted human myoblasts into immunodeficient mice correlates with increased proliferation and migration.Molecular therapy : the journal of the American Society of Gene Therapy · 2012Article
- The role of cremaster muscle in testicular descent in humans and animal models.Pediatric surgery international · 2011Review
- Neurofibromin (Nf1) is required for skeletal muscle development.Human molecular genetics · 2011Article
- Sox6, jack of all trades: a versatile regulatory protein in vertebrate development.Developmental dynamics : an official publication of the American Association of Anatomists · 2011Review
- VAMP2 marks quiescent satellite cells and myotubes, but not activated myoblasts.Acta histochemica et cytochemica · 2010Article
- Quadruplex structures of muscle gene promoter sequences enhance in vivo MyoD-dependent gene expression.Nucleic acids research · 2010Article
- Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling.PloS one · 2009Article
- Retinoid signaling is involved in governing the waiting period for axons in chick hindlimb.Developmental biology · 2008Article
- Muscle development and obesity: Is there a relationship?Organogenesis · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The limb myogenic precursors arise by delamination from the lateral dermomyotome in response to signals from the lateral plate mesoderm. They subsequently migrate into the developing limb bud where they switch on the expression of the myogenic regulatory factors, MyoD and Myf5, and coalese to form the dorsal and ventral muscle masses. The myogenic cells subsequently undergo terminal differentiation into slow or fast fibres which have distinct contractile properties determining how a muscle will function. In general, fast fibres contract rapidly with high force and are characterized by the expression of fast myosin heavy chains (MyHC). These fibres are needed for movement. In contrast, slow fibres express slow MyHC, contract slowly and are required for maintenance of posture. This review focuses on the molecular signals that control limb myogenic development from the initial delamination and migration of the premyogenic cells to the ultimate formation of the complex muscle pattern and differentiation of slow and fast fibres.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.