ReviewJournal of anatomy2003
Congenital talipes equinovarus (clubfoot): a disorder of the foot but not the hand.
Review in Journal of anatomy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 134 citations in OpenAlex.
- The role of clubfoot training programmes in low- and middle-income countries: a systematic review.Tropical doctor · 2020Pooled it
- Virtual 3D landmark palpation in clubfoot: feasibility of an innovative standardized morphometric protocol. A preliminary study.BMC musculoskeletal disorders · 2026Article
- MiRNA Expression Profile as a Potential Biomarker for Idiopathic Congenital Talipes Equinovarus: An Exploratory Study.Orthopedic reviews · 2026Article
- An Observational Study on Pre-natal Diagnosis of Congenital Talipes Equinovarus.Journal of orthopaedic case reports · 2025Article
- Identification of novel nutrient sensitive human yolk sac functions required for embryogenesis.Scientific reports · 2024Article
- A Novel Orthoplastic Reconstruction of Relapsed Clubfoot With Total Ankle Arthroplasty.Cureus · 2023Article
- Article
- A 5-years results of the Ponseti method in the treatment of congenital clubfoot: a retrospective study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Current Clubfoot Practices: POSNA Membership Survey.Children (Basel, Switzerland) · 2023Article
- Assessment of the COL9A1 Single Nucleotide Polymorphism with Severity of clubfoot in a paediatric population along with their biological mothers.Journal of clinical orthopaedics and trauma · 2022Article
- Bilateral Pseudoaneurysms Following Percutaneous Achilles Tenotomy for Congenital Talipes Equinovarus.Cureus · 2022Article
- Congenital talipes equinovarus: A literature review.Annals of medicine and surgery (2012) · 2022Review
- Regulation ofFrontiers in pediatrics · 2022Article
- Assessment of awareness and barriers to clubfoot treatment in the Indian scenario.Journal of family medicine and primary care · 2021Article
- Analysis OF C677T polymorphism in methylene tetrahydrofolate reductase (MTHFR) gene as a risk factor for congenital talipes equino varus (CTEV).Journal of clinical orthopaedics and trauma · 2021Article
- Intramuscular injection of Botox causes tendon atrophy by induction of senescence of tendon-derived stem cells.Stem cell research & therapy · 2021Article
- Integrated Bioinformatics Analysis Reveals Potential Pathway Biomarkers and Their Interactions for Clubfoot.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Evaluation of genetic susceptibility of common variants in SOX9 in patients with congenital talipes equinovarus in the Han Chinese population.Journal of orthopaedic surgery and research · 2020Article
- The influence of laterality, sex and family history on clubfoot severity.Journal of children's orthopaedics · 2020Review
- Resistive index and peak systolic velocity for congenital talipes equinovarus: A color Doppler ultrasonography study.Joint diseases and related surgery · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic (non-syndromic) congenital talipes equinovarus, or clubfoot, is a poorly understood but common developmental disorder of the lower limb, which affects at least 2 per 1000 Scottish births (ISD data). It is defined as a fixation of the foot in a hand-like orientation--in adduction, supination and varus--with concomitant soft tissue abnormalities. Despite advances in treatment, disability often persists. The aetiology of the condition has been little studied and is poorly understood. Neurological, muscular, bony, connective tissue and vascular mechanisms have been proposed, but the only firm evidence is that the mildest cases appear to be associated with intra-uterine posture. There is evidence for a genetic contribution to congenital talipes equinovarus aetiology. Its incidence varies with ethnic group, and we found that a family history is present in 24-50% of cases, depending on the population studied. Complex segregation analysis suggests that the most likely inheritance pattern is a single gene of major effect operating against a polygenic background. Possible mechanisms for congenital talipes equinovarus are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.