ArticlePlant physiology2003
Arabidopsis ICX1 is a negative regulator of several pathways regulating flavonoid biosynthesis genes.
Article in Plant physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 66 citations in OpenAlex.
- Rhizobial Symbiosis Enhances Salinity Tolerance in Legumes Through Coordinated Physiological and Molecular Responses: Evidence From Common Vetch and Pea.Plant, cell & environment · 2026Article
- Influence of genetic diversity, drought stress and rhizobial symbiosis on the nutritional quality of common vetch (Vicia sativa L.) grain.Journal of the science of food and agriculture · 2026Article
- Unraveling the genetic and molecular mechanisms of anthocyanin biosynthesis and accumulation in maize kernels.Frontiers in plant science · 2026Review
- Identification of key genes involved in lignin and flavonoid accumulation during Tilia tuan seed maturation.Plant cell reports · 2024Article
- Transcriptional repression ofPlant direct · 2024Article
- Overexpression of the WheatInternational journal of molecular sciences · 2023Article
- Function deficiency of GhOMT1 causes anthocyanidins over-accumulation and diversifies fibre colours in cotton (Gossypium hirsutum).Plant biotechnology journal · 2022Article
- Growth and Biosynthesis of Phenolic Compounds of Canola (Plants (Basel, Switzerland) · 2022Article
- Molecular bases for drought tolerance in common vetch: designing new molecular breeding tools.BMC plant biology · 2020Article
- Functional analysis of GhCHS, GhANR and GhLAR in colored fiber formation of Gossypium hirsutum L.BMC plant biology · 2019Article
- Molecular Mapping and QTL for Expression Profiles of Flavonoid Genes inFrontiers in plant science · 2016Article
- Sugar-hormone cross-talk in anthocyanin biosynthesis.Molecules and cells · 2012Review
- Cytokinins enhance sugar-induced anthocyanin biosynthesis in Arabidopsis.Molecules and cells · 2012Article
- Article
- The introduction of the stilbene synthase gene enhances the natural antiradical activity of Lycopersicon esculentum mill.Molecular and cellular biochemistry · 2006Article
- A UV-B-specific signaling component orchestrates plant UV protection.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
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3 authors at 1 institution in 1 country.
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Abstract
Flavonoid biosynthesis gene expression is controlled by a range of endogenous and environmental signals. The Arabidopsis icx1 (increased chalcone synthase expression 1) mutant has elevated induction of CHS (CHALCONE SYNTHASE) and other flavonoid biosynthesis genes in response to several stimuli. We show that ICX1 is a negative regulator of the cryptochrome 1, phytochrome A, ultraviolet (UV)-B, low temperature, sucrose, and cytokinin induction of CHS expression and/or anthocyanin accumulation, demonstrating that these pathways are regulated either directly or indirectly by at least one common component. Expression analysis of CHS and other genes (LTP, CAB, and rbcS) indicates that ICX1 functions in both seedlings and mature leaf tissue and acts principally in the epidermis, consistent with the alterations in epidermal development seen in icx1. The mutant was unaltered in the synergistic interactions between UV-B, blue, and UV-A light that regulate CHS and we propose a model of action of ICX1 in these responses.
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