ArticleGenetics2003
Population genetics of Caenorhabditis elegans: the paradox of low polymorphism in a widespread species.
Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 104 citations in OpenAlex.
- T2T genomes ofGenome research · 2026Article
- Global genomic diversity of the selfing nematodebioRxiv : the preprint server for biology · 2026Article
- Pervasive Conservation of Intron Number and Other Genetic Elements Revealed by a Chromosome-level Genome Assembly of the Hyper-polymorphic Nematode Caenorhabditis brenneri.Genome biology and evolution · 2025Article
- Pervasive conservation of intron number and other genetic elements revealed by a chromosome-level genomic assembly of the hyper-polymorphic nematodebioRxiv : the preprint server for biology · 2024Article
- CaeNDR, the Caenorhabditis Natural Diversity Resource.Nucleic acids research · 2024Article
- Genomic diversity landscapes in outcrossing and selfing Caenorhabditis nematodes.PLoS genetics · 2023Article
- Bergerac strains of Caenorhabditis elegans revisited: expansion of Tc1 elements imposes a significant genomic and fitness cost.G3 (Bethesda, Md.) · 2022Article
- Natural variation inGenome research · 2022Article
- Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans.Nature ecology & evolution · 2021Article
- To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq.Nucleic acids research · 2021Article
- Population genomics of Vibrionaceae isolated from an endangered oasis reveals local adaptation after an environmental perturbation.BMC genomics · 2020Article
- Article
- Turnover in local parasite populations temporarily favors host outcrossing over self-fertilization during experimental evolution.Ecology and evolution · 2018Article
- Experimental Evolution withGenetics · 2017Review
- Selection on Position of Nonsense Codons in Introns.Genetics · 2016Article
- Inverse correlation between longevity and developmental rate among wild C. elegans strains.Aging · 2016Article
- Article
- Omega-3 and -6 fatty acids allocate somatic and germline lipids to ensure fitness during nutrient and oxidative stress in Caenorhabditis elegans.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Ten years of life in compost: temporal and spatial variation of North German Caenorhabditis elegans populations.Ecology and evolution · 2015Article
- Full-genome evolutionary histories of selfing, splitting, and selection in Caenorhabditis.Genome research · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Caenorhabditis elegans has become one of the most widely used model research organisms, yet we have little information on evolutionary processes and recent evolutionary history of this widespread species. We examined patterns of variation at 20 microsatellite loci in a sample of 23 natural isolates of C. elegans from various parts of the world. One-half of the loci were monomorphic among all strains, and overall genetic variation at microsatellite loci was low, relative to most other species. Some population structure was detected, but there was no association between the genetic and geographic distances among different natural isolates. Thus, despite the nearly worldwide occurrence of C. elegans, little evidence was found for local adaptation in strains derived from different parts of the world. The low levels of genetic variation within and among populations suggest that recent colonization and population expansion might have occurred. However, the patterns of variation are not consistent with population expansion. A possible explanation for the observed patterns is the action of background selection to reduce polymorphism, coupled with ongoing gene flow among populations worldwide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.