ReviewCellular and molecular neurobiology2002
Brain oscillations, medium spiny neurons, and dopamine.
Review in Cellular and molecular neurobiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed.
- UBE3A expression during early postnatal brain development is required for proper dorsomedial striatal maturation.JCI insight · 2023Article
- Acupuncture Regulates Symptoms of Parkinson's DiseaseFrontiers in aging neuroscience · 2022Article
- Synchronized activation of striatal direct and indirect pathways underlies the behavior in unilateral dopamine-depleted mice.The European journal of neuroscience · 2019Article
- Electrophysiological and Neurochemical Considerations of Distinct Neuronal Populations in the Rat Pedunculopontine Nucleus and Their Responsiveness Following 6-Hydroxydopamine Lesions.Frontiers in neuroscience · 2019Article
- Neurodegenerative diseases: model organisms, pathology and autophagy.Journal of genetics · 2018Review
- Frequency-Dependent Corticostriatal Disinhibition Resulting from Chronic Dopamine Depletion: Role of Local Striatal cGMP and GABA-AR Signaling.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Rewarding Effects of Operant Dry-Licking Behavior on Neuronal Firing in the Nucleus Accumbens Core.Frontiers in pharmacology · 2017Article
- Ventral Medial Thalamic Nucleus Promotes Synchronization of Increased High Beta Oscillatory Activity in the Basal Ganglia-Thalamocortical Network of the Hemiparkinsonian Rat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Deep Brain Stimulation for Movement Disorders of Basal Ganglia Origin: Restoring Function or Functionality?Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2016Review
- Quantitative activation-induced manganese-enhanced MRI reveals severity of Parkinson's disease in mice.Scientific reports · 2015Article
- The presence of cortical neurons in striatal-cortical co-cultures alters the effects of dopamine and BDNF on medium spiny neuron dendritic development.Frontiers in cellular neuroscience · 2015Article
- Preserving cortico-striatal function: deep brain stimulation in Huntington's disease.Frontiers in systems neuroscience · 2015Article
- Functional correlates of exaggerated oscillatory activity in basal ganglia output in hemiparkinsonian rats.Experimental neurology · 2014Article
- An adaptive role of TNFα in the regulation of striatal synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Oscillatory Activity in Basal Ganglia and Motor Cortex in an Awake Behaving Rodent Model of Parkinson's Disease.Basal ganglia · 2014Article
- GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity.Frontiers in cellular neuroscience · 2014Article
- Processing of sub- and supra-second intervals in the primate brain results from the calibration of neuronal oscillators via sensory, motor, and feedback processes.Frontiers in psychology · 2014Article
- Dopamine control of pyramidal neuron activity in the primary motor cortex via D2 receptors.Frontiers in neural circuits · 2014Article
- Haloperidol-induced changes in neuronal activity in the striatum of the freely moving rat.Frontiers in systems neuroscience · 2013Article
- State-dependent spike and local field synchronization between motor cortex and substantia nigra in hemiparkinsonian rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. The striatum is part of a multisynaptic loop involved in translating higher order cognitive activity into action. The main striatal computational unit is the medium spiny neuron, which integrates inputs arriving from widely distributed cortical neurons and provides the sole striatal output. 2. The membrane potential of medium spiny neurons' displays shifts between a very negative resting state (down state) and depolarizing plateaus (up states) which are driven by the excitatory cortical inputs. 3. Because striatal spiny neurons fire action potentials only during the up state, these plateau depolarizations are perceived as enabling events that allow information processing through cerebral cortex-basal ganglia circuits. In vivo intracellular recording techniques allow to investigate simultaneously the subthreshold behavior of the medium spiny neuron membrane potential (which is a "reading" of distributed patterns of cortical activity) and medium spiny neuron firing (which is an index of striatal output). 4. Recent studies combining intracellular recordings of striatal neurons with field potential recordings of the cerebral cortex illustrate how the analysis of the input-output transformations performed by medium spiny neurons may help to unveil some aspects of information processing in cerebral cortex-basal ganglia circuits, and to understand the origin of the clinical manifestations of Parkinson's disease and other neurologic and neuropsychiatric disorders that result from alterations in dopamine-dependent information processing in the cerebral cortex-basal ganglia circuits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.