ArticleEnvironmental health perspectives2003
Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population.
Article in Environmental health perspectives, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 297 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
297 citing papers in PubMed, 6 syntheses or guidelines pooled it, 617 citations in OpenAlex.
- Dietary Polycyclic Aromatic Hydrocarbon (PAH) Consumption and Risk of Adverse Birth Outcomes: A Systematic Review and Meta-Analysis.Environmental health perspectives · 2024Pooled it
- Towards Integrated Air Pollution Monitoring and Health Impact Assessment Using Federated Learning: A Systematic Review.Frontiers in public health · 2022Pooled it
- The association between prenatal exposure to polycyclic aromatic hydrocarbons and birth weight: A meta-analysis.PloS one · 2020Pooled it
- Indoor exposure and adverse birth outcomes related to fetal growth, miscarriage and prematurity-a systematic review.International journal of environmental research and public health · 2014Pooled it
- Pesticide exposure and neurodevelopmental outcomes: review of the epidemiologic and animal studies.Journal of toxicology and environmental health. Part B, Critical reviews · 2013Pooled it
- Ambient air pollution and risk of congenital anomalies: a systematic review and meta-analysis.Environmental health perspectives · 2011Pooled it
- Polycyclic aromatic hydrocarbons and perinatal outcomes: a scoping review.Pediatric research · 2026Review
- Joint impact of prenatal polycyclic aromatic hydrocarbons, anxiety and depression exposure on birth outcomes across pre-pregnancy BMI categories.Journal of exposure science & environmental epidemiology · 2026Article
- Recreational physical activity and biomarkers of breast cancer risk in a cohort of adolescent girls.Breast cancer research : BCR · 2026Article
- Combined prenatal exposure to airborne polycyclic aromatic hydrocarbons and maternal distress is associated with childhood irritability.Frontiers in public health · 2026Article
- Prenatal environmental risk for adolescent attention, thought, and substance use problems: A mixtures approach to coexposure and psychiatric comorbidities.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Mitochondrial DNA copy number and neurocognitive outcomes in children.Pediatric research · 2025Article
- Prenatal organophosphate pesticide exposure and sex-specific estimated fetal size.American journal of epidemiology · 2025Article
- EndoCompass Project: Environmental Endocrinology.Hormone research in paediatrics · 2025Review
- An evaluation of in utero polycyclic aromatic hydrocarbon exposure on the neonatal meconium microbiome.Environmental research · 2024Article
- Reduction in polycyclic aromatic hydrocarbon exposure in Beijing following China's clean air actions.Science bulletin · 2024Article
- Effects of maternal exposure to biomass cooking fuel on birth size and body proportionality in full-term infants born by vaginal delivery.Scientific reports · 2024Article
- Trajectory analysis of rhinitis in a birth cohort from lower-income New York City neighborhoods.The Journal of allergy and clinical immunology · 2024Article
- Urinary 1-hydroxypyrene in pregnant women in a Northeastern U.S. city: socioeconomic disparity and contributions from air pollution sources.Journal of exposure science & environmental epidemiology · 2024Article
- The effects of inhaled pollutants on reproduction in marginalized communities: a contemporary review.Inhalation toxicology · 2024Review
237 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Inner-city, minority populations are high-risk groups for adverse birth outcomes and also are more likely to be exposed to environmental contaminants, including environmental tobacco smoke (ETS), polycyclic aromatic hydrocarbons (PAHs), and pesticides. In a sample of 263 nonsmoking African-American and Dominican women, we evaluated the effects on birth outcomes of prenatal exposure to airborne PAHs monitored during pregnancy by personal air sampling, along with ETS estimated by plasma cotinine, and an organophosphate pesticide (OP) estimated by plasma chlorpyrifos (CPF). Plasma CPF was used as a covariate because it was the most often detected in plasma and was highly correlated with other pesticides frequently detected in plasma. Among African Americans, high prenatal exposure to PAHs was associated with lower birth weight (p = 0.003) and smaller head circumference (p = 0.01) after adjusting for potential confounders. CPF was associated with decreased birth weight and birth length overall (p = 0.01 and p = 0.003, respectively) and with lower birth weight among African Americans (p = 0.04) and reduced birth length in Dominicans (p < 0.001), and was therefore included as a covariate in the model with PAH. After controlling for CPF, relationships between PAHs and birth outcomes were essentially unchanged. In this analysis, PAHs and CPF appear to be significant independent determinants of birth outcomes. Further analyses of pesticides will be carried out. Possible explanations of the failure to find a significant effect of PAHs in the Hispanic subsample are discussed. This study provides evidence that environmental pollutants at levels currently encountered in New York City adversely affect fetal development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.