ArticleThe Plant cell2003
The maize genome contains a helitron insertion.
Article in The Plant cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 121 citations in OpenAlex.
- Chromosome-level phylogenomics and genome evolution of the grape family.Nature plants · 2026Article
- The role of mobile DNA elements in the dynamics of plant genome plasticity.Journal of experimental botany · 2025Review
- Abundance of Transgene Transcript Variants Associated with Somatically Active TransgenicInternational journal of molecular sciences · 2023Article
- The multiple fates of gene duplications: Deletion, hypofunctionalization, subfunctionalization, neofunctionalization, dosage balance constraints, and neutral variation.The Plant cell · 2022Article
- Allelic variation in shrunken2 gene affecting kernel sweetness in exotic-and indigenous-maize inbreds.PloS one · 2022Article
- A helitron-induced RabGDIα variant causes quantitative recessive resistance to maize rough dwarf disease.Nature communications · 2020Article
- Somatic transposition and meiotically driven elimination of an active helitron family in Pleurotus ostreatus.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Helitron-like transposons contributed to the mating system transition from out-crossing to self-fertilizing in polyploid Brassica napus L.Scientific reports · 2016Article
- A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.Nature communications · 2016Article
- Review
- Differential pre-mRNA Splicing Alters the Transcript Diversity of Helitrons Between the Maize Inbred Lines.G3 (Bethesda, Md.) · 2015Article
- The sh2-R allele of the maize shrunken-2 locus was caused by a complex chromosomal rearrangement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Article
- Mining hidden polymorphic sequence motifs from divergent plantMobile genetic elements · 2014Article
- Rolling-circle transposons catalyze genomic innovation in a mammalian lineage.Genome biology and evolution · 2014Article
- HelitronScanner uncovers a large overlooked cache of Helitron transposons in many plant genomes.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Comparative analysis of syntenic genes in grass genomes reveals accelerated rates of gene structure and coding sequence evolution in polyploid wheat.Plant physiology · 2013Article
- Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels.Nature genetics · 2013Article
- Editor's choice: Crop genome plasticity and its relevance to food and feed safety of genetically engineered breeding stacks.Plant physiology · 2012Review
- Identification, characterization and distribution of transposable elements in the flax (Linum usitatissimum L.) genome.BMC genomics · 2012Article
3 more citing papers are in PubMed but not listed here.
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5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The maize mutation sh2-7527 was isolated in a conventional maize breeding program in the 1970s. Although the mutant contains foreign sequences within the gene, the mutation is not attributable to an interchromosomal exchange or to a chromosomal inversion. Hence, the mutation was caused by an insertion. Sequences at the two Sh2 borders have not been scrambled or mutated, suggesting that the insertion is not caused by a catastrophic reshuffling of the maize genome. The insertion is large, at least 12 kb, and is highly repetitive in maize. As judged by hybridization, sorghum contains only one or a few copies of the element, whereas no hybridization was seen to the Arabidopsis genome. The insertion acts from a distance to alter the splicing of the sh2 pre-mRNA. Three distinct intron-bearing maize genes were found in the insertion. Of most significance, the insertion bears striking similarity to the recently described DNA helicase-bearing transposable elements termed HELITRONS: Like Helitrons, the inserted sequence of sh2-7527 is large, lacks terminal repeats, does not duplicate host sequences, and was inserted between a host dinucleotide AT. Like Helitrons, the maize element contains 5' TC and 3' CTRR termini as well as two short palindromic sequences near the 3' terminus that potentially can form a 20-bp hairpin. Although the maize element lacks sequence information for a DNA helicase, it does contain four exons with similarity to a plant DEAD box RNA helicase. A second Helitron insertion was found in the maize genomic database. These data strongly suggest an active Helitron in the present-day maize genome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.