ArticleThe Plant cell2003
The Arabidopsis cax1 mutant exhibits impaired ion homeostasis, development, and hormonal responses and reveals interplay among vacuolar transporters.
Article in The Plant cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
95 citing papers in PubMed, 224 citations in OpenAlex.
- CAX1 beyond calcium transport: evidence for a transport-independent regulatory module in plants.Frontiers in plant science · 2026Review
- Molecular basis of delayed BSMYV infection in diploid Musa balbisiana, a banana progenitor.Molecular biology reports · 2025Article
- Rapid acquisition of ionomic and morphological data from plant seeds through fast X-ray fluorescence microscopy and computer vision.Plant phenomics (Washington, D.C.) · 2025Article
- OsCAX1a-Dependent Ca-Mg Balance Is Required for Optimal Growth in Rice.Rice (New York, N.Y.) · 2025Article
- Lithium in plants.The New phytologist · 2025Review
- Time-Series Elemental Imaging Reveals CAX-Dependent Redistribution Patterns for Anoxia Recovery.Journal of experimental botany · 2025Article
- Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2025Article
- Functional differentiation and genetic diversity of rice cation exchanger (CAX) genes and their potential use in rice improvement.Scientific reports · 2024Article
- Golgi apparatus-localized CATION CALCIUM EXCHANGER4 promotes osmotolerance of Arabidopsis.Plant physiology · 2024Article
- Auxin as an architect of the pectin matrix.Journal of experimental botany · 2023Review
- Beyond NPK: Mineral Nutrient-Mediated Modulation in Orchestrating Flowering Time.Plants (Basel, Switzerland) · 2023Review
- Genome-Wide Identification ofGenes · 2023Article
- Cadmium Transport in Maize Root Segments Using a Classical Physiological Approach: Evidence of Influx Largely Exceeding Efflux in Subapical Regions.Plants (Basel, Switzerland) · 2023Article
- Physiological and Transcriptional Responses ofInternational journal of molecular sciences · 2023Article
- Generating Reproducing Anoxia Conditions for Plant Phenotyping.Bio-protocol · 2023Article
- The vacuolar H+/Ca transporter CAX1 participates in submergence and anoxia stress responses.Plant physiology · 2022Article
- Long-distance mobile mRNA CAX3 modulates iron uptake and zinc compartmentalization.EMBO reports · 2022Article
- Calcium channels and transporters: Roles in response to biotic and abiotic stresses.Frontiers in plant science · 2022Review
- The Plant V-ATPase.Frontiers in plant science · 2022Review
- Transcriptomic Profiling Provides Molecular Insights Into Hydrogen Peroxide-EnhancedFrontiers in plant science · 2022Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
The Arabidopsis Ca(2+)/H(+) transporter CAX1 (Cation Exchanger1) may be an important regulator of intracellular Ca(2+) levels. Here, we describe the preliminary localization of CAX1 to the tonoplast and the molecular and biochemical characterization of cax1 mutants. We show that these mutants exhibit a 50% reduction in tonoplast Ca(2+)/H(+) antiport activity, a 40% reduction in tonoplast V-type H(+)-translocating ATPase activity, a 36% increase in tonoplast Ca(2+)-ATPase activity, and increased expression of the putative vacuolar Ca(2+)/H(+) antiporters CAX3 and CAX4. Enhanced growth was displayed by the cax1 lines under Mn(2+) and Mg(2+) stress conditions. The mutants exhibited altered plant development, perturbed hormone sensitivities, and altered expression of an auxin-regulated promoter-reporter gene fusion. We propose that CAX1 regulates myriad plant processes and discuss the observed phenotypes with regard to the compensatory alterations in other transporters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.