ReviewThe Journal of cell biology2003
LIS1 at the microtubule plus end and its role in dynein-mediated nuclear migration.
Review in The Journal of cell biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 33 citations in OpenAlex.
- LncRNA RASAL2-AS1 promotes METTL14-mediated m6A methylation in the proliferation and progression of head and neck squamous cell carcinoma.Cancer cell international · 2024Article
- Dynein Heavy Chain, Encoded by Two Genes in Agaricomycetes, Is Required for Nuclear Migration in Schizophyllum commune.PloS one · 2015Article
- Quantitative analysis of Pac1/LIS1-mediated dynein targeting: Implications for regulation of dynein activity in budding yeast.Cytoskeleton (Hoboken, N.J.) · 2011Article
- Controlled and stochastic retention concentrates dynein at microtubule ends to keep endosomes on track.The EMBO journal · 2011Article
- Lis1/dynactin regulates metaphase spindle orientation in Drosophila neuroblasts.Developmental biology · 2008Article
- Regulation of cytoplasmic dynein ATPase by Lis1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?Retrovirology · 2005Article
- +TIPs and microtubule regulation. The beginning of the plus end in plants.Plant physiology · 2004Review
- Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration.The Journal of cell biology · 2004Article
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1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cytoplasmic dynein complex and its accessory dynactin complex are involved in many cellular activities including nuclear migration in fungi (for review see Karki and Holzbaur, 1999). LIS1, the product of a causal gene for human lissencephaly (smooth brain), has also been implicated in dynein function based on studies in fungi and more recent studies in higher eukaryotic systems (for review see Gupta et al., 2002). Exactly how LIS1 may regulate the behavior of cytoplasmic dynein in various organisms is a fascinating question. In this issue, Lee et al. (2003) describe important new findings in Saccharomyces cerevisiae regarding the role of LIS1 (Pac1) in dynein-mediated nuclear migration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.