ArticleThe Journal of physiology2003
Arm blood flow and oxygenation on the transition from arm to combined arm and leg exercise in humans.
Article in The Journal of physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 43 citations in OpenAlex.
- Upper but not lower limb resistance training increases arterial stiffness in humans.European journal of applied physiology · 2009Trial
- Inhibition of alpha-adrenergic vasoconstriction in exercising human thigh muscles.The Journal of physiology · 2004Trial
- The effect of work rate on metabolic and mechanical intensity measures across skating style sub-techniques in cross-country skiing.European journal of sport science · 2025Article
- A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise.Experimental physiology · 2025Review
- Effects of Upper Body Exercise Training on Aerobic Fitness and Performance in Healthy People: A Systematic Review.Biology · 2023Review
- Review
- Matching of OFrontiers in physiology · 2022Review
- The physiology of rowing with perspective on training and health.European journal of applied physiology · 2020Review
- Muscle Oxygen Delivery in the Forearm and in theFrontiers in physiology · 2020Article
- Cardiovascular control during whole body exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2016Review
- Physiological Demands of Simulated Off-Road Cycling Competition.Journal of sports science & medicine · 2015Article
- Dynamics of muscle microcirculatory and blood-myocyte O(2) flux during contractions.Acta physiologica (Oxford, England) · 2011Review
- Disparity in regional and systemic circulatory capacities: do they affect the regulation of the circulation?Acta physiologica (Oxford, England) · 2010Review
- Maximal muscular vascular conductances during whole body upright exercise in humans.The Journal of physiology · 2004Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cardiovascular response to exercise with several groups of skeletal muscle implies that work with the legs may reduce arm blood flow. This study followed arm blood flow (Yarm) and oxygenation on the transition from arm cranking (A) to combined arm and leg exercise (A+L). Seven healthy male subjects performed A at approximately 80 % of maximum work rate (Wmax) and A at ~80 % Wmax combined with L at approximately 60 % Wmax. A transition trial to volitional exhaustion was performed where L was added after 2 min of A. The Yarm was determined by constant infusion thermodilution in the axillary vein and changes in biceps muscle oxygenation were measured with near-infrared spectroscopy. During A+L Yarm was lowered by 0.38 +/- 0.06 l min-1 (10.4 +/- 3.3 %, P < 0.05) from 2.96 +/- 1.54 l min-1 during A. Total (HbT) and oxygenated haemoglobin (HbO2) concentrations were also lower. During the transition from A to A+L Yarm decreased by 0.22 +/- 0.03 l min-1 (7.9 +/- 1.8 %, P < 0.05) within 9.6 +/- 0.2 s, while HbT and HbO2 decreased similarly within 30 +/- 2 s. At the same time mean arterial pressure and arm vascular conductance also decreased. The data demonstrate reduction in blood flow to active skeletal muscle during maximal whole body exercise to a degree that arm oxygen uptake and muscle tissue oxygenation are compromised.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.