Evidence map›Paper›PMID 12560946›Full record

Trial reportEuropean journal of applied physiology2003

Relationship between in vivo muscle force at different speeds of isokinetic movements and myosin isoform expression in men and women.

H Gür, L Gransberg, D vanDyke, E Knutsson, L Larsson

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H GürDepartment of Sports Medicine, Medical School of Uludag University, Bursa, Turkey.
L Gransberg
D vanDyke
E Knutsson
L Larsson

Funding

SHORTENING VELOCITY AND SCALING:UNDERLYING MECHANISMSR01AR047318 · NIAMS · UPPSALA UNIVERSITY · PI LARSSON, LARS G · 2001 to 2005
$1.3M
SARCOPENIA--UNDERLYING MECHANISMSR01AR045627 · NIAMS · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI DWORKIN, BARRY R · 2000 to 2003
$1.3M
NIAMS NIH HHS AR 45627NIAMS NIH HHS AR47318
6 · The paper itself

Abstract

In an attempt to explore the relationship between force production during voluntary contractions at different speeds of isokinetic movement and the myofibrillar protein isoform expression in humans, an improved isokinetic dynamometer that corrects for gravitation, controls for acceleration and deceleration, and identifies a maximum voluntary activation was used. Muscle torque recordings were compared at the same muscle length (knee angle) and the torque was calculated as the average torque at each angle over a large knee angle range (75 degrees -25 degrees ) to reduce the influence of small torque oscillation on the calculated torque. Muscle torque at fast (240 degrees s(-1)) versus slow (30 degrees s(-1)) speeds of movement, torque normalized to muscle cross-sectional area (specific tension), and absolute torque at fast speeds of movement were measured in 34 young healthy male and female short-, middle-, and long-distance runners. The relationship between the different measures of muscle function and the expression of myosin heavy chain (MyHC) isoforms using enzyme-histochemical and electrophoretic protein separation techniques were investigated. A significant correlation between the 240 degrees s(-1) vs 30 degrees s(-1) torque ratio and the relative area of the type II fibers and type II MyHC isoforms were observed in both the men (r=0.74; P<0.001) and the women (r=0.81; P<0.05). Thus, the present results confirm a significant relationship between in vivo human muscle function and the MyHC isoform expression in the contracting muscle.

Indexed as

AdolescentAdultExercise TestFemaleHumansKneeMaleMovementMuscle ContractionMuscle, SkeletalMyosin Heavy ChainsPhysical ExertionProtein IsoformsReproducibility of ResultsSensitivity and SpecificitySex FactorsMyosin Heavy ChainsProtein Isoforms

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.