ReviewThorax2003
Pharmacotherapy and airway remodelling in asthma?
Review in Thorax, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Trial
- Steroids reduce local inflammatory mediator secretion and mucosal permeability in collagenous colitis patients.World journal of gastroenterology · 2006Trial
- A randomized clinical trial of peak flow versus symptom monitoring in older adults with asthma.American journal of respiratory and critical care medicine · 2006Trial
- Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthma.Respiratory research · 2024Article
- Pharmacological Properties of 2,4,6-Trihydroxy-3-Geranyl Acetophenone and the Underlying Signaling Pathways: Progress and Prospects.Frontiers in pharmacology · 2021Review
- IL-32γ attenuates airway fibrosis by modulating the integrin-FAK signaling pathway in fibroblasts.Respiratory research · 2018Article
- Article
- Bronchoconstriction Induces Structural and Functional Airway Alterations in Non-sensitized Rats.Lung · 2017Article
- Airway remodeling in asthma: what really matters.Cell and tissue research · 2017Review
- Airway Remodeling in Chronic Obstructive Pulmonary Disease and Asthma: the Role of Matrix Metalloproteinase-9.Archivum immunologiae et therapiae experimentalis · 2016Review
- Statins in Asthma: Potential Beneficial Effects and Limitations.Pulmonary medicine · 2015Review
- Lost to follow-up in asthmatics does not mean treatment failure: causes and clinical outcomes of non-adherence to outpatient treatment in adult asthma.Allergy, asthma & immunology research · 2013Article
- Corticosteroid administration reduces the concentration of hyaluronan in bronchoalveolar lavage in a murine model of eosinophilic airway inflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Article
- Role of hyaluronan and hyaluronan-binding proteins in human asthma.The Journal of allergy and clinical immunology · 2011Article
- Airway remodeling: a potential therapeutic target in asthma.World journal of pediatrics : WJP · 2011Review
- Pharmacologic modulation of experimentally induced allergic asthma.Interdisciplinary toxicology · 2011Article
- High-resolution computed tomography evaluation of airway distensibility in asthmatic and healthy subjects.La Radiologia medica · 2008Article
- Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling.The American journal of pathology · 2006Article
- Prolonged ozone exposure in an allergic airway disease model: adaptation of airway responsiveness and airway remodeling.Respiratory research · 2006Article
- Inhaled corticosteroids and decline of lung function in community residents with asthma.Thorax · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last few decades attention has largely focused on airway inflammation in asthma, but more recently it has been appreciated that there are important structural airway changes which have been grouped together under the term "airway remodelling". It is only now that questions have been asked about the impact of treatment on these structural changes. This review examines the nature of these structural airway changes, the mechanisms of their generation, their potential consequences, and what is known about the ability of anti-asthma treatments to modulate these changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.