Evidence map›Paper›PMID 12554890›Full record

Trial reportThorax2003

Breathing retraining for dysfunctional breathing in asthma: a randomised controlled trial.

M Thomas, R K McKinley, E Freeman, C Foy, P Prodger, D Price

Registry-linked trialOpen access · bronzeAbstract readClinical TrialComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Thorax, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07397676 (Effects of Breathing Technique Training and Physical Activity Counseling on Quality of Life, Symptoms, Asthma Control, and Physical Activity in Children and Adolescents With Asthma), which is not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07397676 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Effects of Breathing Technique Training and Physical Activity Counseling on Quality of Life, Symptoms, Asthma Control, and Physical Activity in Children and Adolescents With Asthma: A Randomized Controlled Trial

TypeinterventionalSponsorKarolinska University HospitalRan2024 to 2026Enrolled40ConditionsPaediatric Asthma, Paediatric Dysfunctional BreathingArmsBreathing training, Standrad advice about physical activity
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 226 citations in OpenAlex.

  1. Breathing exercises for adults with asthma.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Yoga for asthma.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Yoga Therapy as an Adjuvant in Management of Asthma.Indian journal of pediatrics · 2021
    Trial
  7. Trial
  8. The BREATHE study: Breathing REtraining for Asthma--Trial of Home Exercises. a protocol summary of a randomised controlled trial.Primary care respiratory journal : journal of the General Practice Airways Group · 2013
    Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Optimal Treatment for Dysfunctional Breathing in Adults: An International Delphi Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

M ThomasDepartment of Primary Care, University of Aberdeen, Aberdeen, UK. mikethomas@doctors.org.uk
R K McKinley
E Freeman
C Foy
P Prodger
D Price
University of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional breathing disorders may complicate asthma and impair quality of life. This study aimed to determine the effectiveness of physiotherapy based breathing retraining for patients treated for asthma in the community who have symptoms suggestive of dysfunctional breathing.

methods33 adult patients aged 17-65 with diagnosed and currently treated asthma and Nijmegen questionnaire scores > or =23 were recruited to a randomised controlled trial comparing short physiotherapy breathing retraining and an asthma nurse education control. The main outcome measures were asthma specific health status (Asthma Quality of Life questionnaire) and Nijmegen questionnaire scores

resultsOf the 33 who entered the study, data were available on 31 after 1 month and 28 at 6 months. The median (interquartile range) changes in overall asthma quality of life score at 1 month were 0.6 (0.05-1.12) and 0.09 (-0.25-0.26) for the breathing retraining and education groups, respectively (p=0.018), 0.42 (0.11-1.17) and 0.09 (-0.58-0.5) for the symptoms domain (p=0.042), 0.52 (0.09-1.25) and 0 (-0.45-0.45) for the activities domain (p=0.007), and 0.50 (0-1.50) and -0.25 (-0.75-0.75) for the environment domain (p=0.018). Only the change in the activities domain remained significant at 6 months (0.83 (-0.10-1.71) and -0.05 (-0.74-0.34), p=0.018), although trends to improvement were seen in the overall score (p=0.065), the symptoms domain (p=0.059), and the environment domain (p=0.065). There was a correlation between changes in quality of life scores and Nijmegen questionnaire scores at 1 month and at 6 months. The number needed to treat to produce a clinically important improvement in health status was 1.96 and 3.57 at 1 and 6 months.

conclusionOver half the patients treated for asthma in the community who have symptoms suggestive of dysfunctional breathing show a clinically relevant improvement in quality of life following a brief physiotherapy intervention. This improvement is maintained in over 25% 6 months after the intervention.

Indexed as

Administration, InhalationAdolescentAdultAgedAlgorithmsAnti-Asthmatic AgentsAsthmaFemaleHumansMaleMiddle AgedPatient Education as TopicPeak Expiratory Flow RatePhysical Therapy ModalitiesQuality of LifeRespiration DisordersAnti-Asthmatic Agents

Identifiers

PMID12554890
PMCPMC1746567
OpenAlexW2141006215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.