ArticleThe EMBO journal2003
Low temperature inhibits RNA silencing-mediated defence by the control of siRNA generation.
Article in The EMBO journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.
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Who cites it
186 citing papers in PubMed, 495 citations in OpenAlex.
- Tobamoviruses: Advances in Molecular Biology, Host Interactions and Integrated Disease Management.Biology · 2026Review
- Thermotherapy Treatments of Fruit Trees of the Genus Prunus Infected by Viruses and Bacteria.Plants (Basel, Switzerland) · 2026Article
- Blurred Boundaries: Functional Overlap Between Coat Protein and 30K Movement Proteins in Systemic Movement.The plant pathology journal · 2026Review
- Mutation of AV2 Start Codon Impairs the Infectivity of a Bipartite Begomovirus Under High Temperature.The plant pathology journal · 2026Article
- Virus-induced genome editing enables functional genomics across diverse plant species.Molecules and cells · 2026Review
- Competition for Chaperones: A Trade-Off Between Thermotolerance and Antiviral Immunity in Plants.Current issues in molecular biology · 2025Review
- Thermotolerance elicits specific genes in cucurbit plants as a response to the combined effect of viral infection and temperature stress.Journal of experimental botany · 2025Article
- Elevated Temperature Can Reduce Cucumber Mosaic Virus Transmission in Tobacco Plants by Altering the Insect Vector's Performance.The plant pathology journal · 2025Article
- Virus-induced gene editing free from tissue culture.Nature plants · 2025Review
- Viral tropism in plants, reproductive tissues, and seeds.Archives of microbiology · 2025Review
- Cold suppresses virus accumulation and alters the host transcriptomic response in the turnip mosaic virus-Arabidopsis halleri system.Plant & cell physiology · 2025Article
- Enhancing virus-mediated genome editing for cultivated tomato through low temperature.Plant cell reports · 2025Article
- Genomic insights into host-associated variants and transmission features of a ToBRFV isolate from Mexico.Frontiers in plant science · 2025Article
- Viroid ecology in hops (Frontiers in microbiology · 2025Article
- Optimizing greenhouse microclimate for plant pathology: challenges and cooling solutions for pathogen control in arid regions.Frontiers in plant science · 2025Review
- Assessing the efficacy of thermotherapy combined with chemotherapy or cryotherapy for the eradication of grapevine leafroll-associated virus 3.Frontiers in plant science · 2025Article
- Heritable gene editing in tomato through viral delivery of isopentenyl transferase and single-guide RNAs to latent axillary meristematic cells.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The Elimination of Viroids through In Vitro Thermotherapy and a Meristem Tip Culture from a New Limonime Hybrid (Biotech (Basel (Switzerland)) · 2024Article
- Transgenic expression of artificial microRNA targeting soybean mosaic virus P1 gene confers virus resistance in plant.Transgenic research · 2024Article
- Efficient RNAi knockdown at 20 °C in Aedes albopictus (Diptera: Culicidae).Journal of medical entomology · 2024Article
126 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temperature dramatically affects plant-virus interactions. Outbreaks of virus diseases are frequently associated with low temperature, while at high temperature viral symptoms are often attenuated (heat masking) and plants rapidly recover from virus diseases. However, the underlying mechanisms of these well-known observations are not yet understood. RNA silencing is a conserved defence system of eukaryotic cells, which operates against molecular parasites including viruses and transgenes. Here we show that at low temperature both virus and transgene triggered RNA silencing are inhibited. Therefore, in cold, plants become more susceptible to viruses, and RNA silencing-based phenotypes of transgenic plants are lost. Consistently, the levels of virus- and transgene-derived small (21-26 nucleotide) interfering (si) RNAs-the central molecules of RNA silencing-mediated defence pathways-are dramatically reduced at low temperature. In contrast, RNA silencing was activated and the amount of siRNAs gradually increased with rising temperature. However, temperature does not influence the accumulation of micro (mi) RNAs, which play a role in developmental regulation, suggesting that the two classes of small (si and mi) RNAs are generated by different nuclease complexes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.