Evidence map›Paper›PMID 12552017›Full record

ArticleJournal of virology2003

Targeted retroviral infection of tumor cells by receptor cooperation.

Francisco Martin, Simon Chowdhury, Stuart J Neil, Kerry A Chester, Francois-Loic Cosset, Mary K Collins

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Polysaccharide-modified scaffolds for controlled lentivirus delivery in vitro and after spinal cord injury.Journal of controlled release : official journal of the Controlled Release Society · 2013
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Francisco MartinDepartment of Immunology and Molecular Pathology, Windeyer Institute, 46 Cleveland Street, London W1T 2AH, United Kingdom.
Simon Chowdhury
Stuart J Neil
Kerry A Chester
Francois-Loic Cosset
Mary K Collins
Institute of Molecular Medicine · INUniversity College London · GBVirologie et Pathologies Humaines · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retroviruses expressing two different receptor-binding domains linked by proline-rich spacers infect only cells expressing both retroviral receptors (Valsesia-Wittman et al., EMBO J. 6:1214-1223, 1997). Here we apply this receptor cooperation strategy to target human tumor cells by linking single-chain antibodies recognizing tumor antigens via proline-rich spacers to the 4070A murine leukemia virus surface protein.

Indexed as

Antibodies, NeoplasmCarcinoembryonic AntigenGenetic VectorsHumansImmunoglobulin FragmentsMembrane GlycoproteinsMoloney murine leukemia virusReceptors, VirusTumor Cells, CulturedAntibodies, NeoplasmCarcinoembryonic Antigenecotropic murine leukemia virus receptorImmunoglobulin FragmentsMembrane GlycoproteinsReceptors, Virus

Identifiers

PMID12552017
PMCPMC141083
OpenAlexW2024203562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.