ArticleJournal of virology2003
Cell penetration and trafficking of polyomavirus.
Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 55 citations in OpenAlex.
- Microtubules in Polyomavirus Infection.Viruses · 2020Review
- Article
- Caveolin- and clathrin-independent entry of BKPyV into primary human proximal tubule epithelial cells.Virology · 2016Article
- Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking.Viruses · 2014Review
- Involvement of microtubular network and its motors in productive endocytic trafficking of mouse polyomavirus.PloS one · 2014Article
- Nuclear actin and lamins in viral infections.Viruses · 2012Review
- Highly dynamic microtubules improve the effectiveness of early stages of human influenza A/NWS/33 virus infection in LLC-MK2 cells.PloS one · 2012Article
- Mechanisms of viral entry: sneaking in the front door.Protoplasma · 2010Review
- Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus.Journal of virology · 2010Article
- Infectious entry of equine herpesvirus-1 into host cells through different endocytic pathways.Virology · 2009Article
- Early events during BK virus entry and disassembly.Journal of virology · 2009Article
- A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum.Journal of cell science · 2008Article
- Imaging single virus particles on the surface of cell membranes by high-resolution scanning surface confocal microscopy.Biophysical journal · 2008Article
- Intracellular trafficking pathway of BK Virus in human renal proximal tubular epithelial cells.Virology · 2008Article
- Caveolar endocytosis is critical for BK virus infection of human renal proximal tubular epithelial cells.Journal of virology · 2007Article
- Murine polyomavirus-like particles induce maturation of bone marrow-derived dendritic cells and proliferation of T cells.Medical microbiology and immunology · 2007Article
- Mouse polyomavirus enters early endosomes, requires their acidic pH for productive infection, and meets transferrin cargo in Rab11-positive endosomes.Journal of virology · 2006Article
- Retrograde transport pathways utilised by viruses and protein toxins.Virology journal · 2006Review
- Involvement of cytoskeletal components in BK virus infectious entry.Journal of virology · 2005Article
- Dynein light chain 1 regulates dynamin-mediated F-actin assembly during sperm individualization in Drosophila.Molecular biology of the cell · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The murine polyomavirus (Py) enters mouse fibroblasts and kidney epithelial cells via an endocytic pathway that is caveola-independent (as well as clathrin-independent). In contrast, uptake of simian virus 40 into the same cells is dependent on caveola. Following the initial uptake of Py, both microtubules and microfilaments play roles in trafficking of the virus to the nucleus. Colcemid, which disrupts microtubules, inhibits the ability of Py to reach the nucleus and replicate. Paclitaxel, which stabilizes microtubules and prevents microtubule turnover, has no effect, indicating that intact but not dynamic microtubules are required for Py infectivity. Compounds that disrupt actin filaments enhance Py uptake while stabilization of actin filaments impedes Py infection. Virus particles are seen in association with actin in cells treated with microfilament-disrupting or filament-stabilizing agents at levels comparable to those in untreated cells, suggesting that a dynamic state of the microfilament system is important for Py infectivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.