Evidence map›Paper›PMID 12548295›Full record

Trial reportEuropean journal of clinical nutrition2003

Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrations.

I Erlund, J Marniemi, P Hakala, G Alfthan, E Meririnne, A Aro

Abstract readClinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biomarkers of Berry Intake: Systematic Review Update.Journal of agricultural and food chemistry · 2023
    Pooled it
  2. Berry meals and risk factors associated with metabolic syndrome.European journal of clinical nutrition · 2010
    Trial
  3. Review
  4. Lingonberry (International journal of molecular sciences · 2021
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Dietary inhibitors of monoamine oxidase A.Journal of neural transmission (Vienna, Austria : 1996) · 2011
    Review
  12. Article
  13. Article
  14. Allergy to lingonberry: A case report.Clinical and molecular allergy : CMA · 2004
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

I ErlundBiomarker Laboratory, National Public Health Institute, Helsinki, Finland. iris.erlund@ktl.fi
J Marniemi
P Hakala
G Alfthan
E Meririnne
A Aro

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study serum quercetin concentrations of subjects consuming berries or habitual Finnish diets.

designRandomized parallel dietary intervention. SUBJECTS: Forty healthy men (age 60 y).

interventionTwenty subjects consumed 100 g/day of berries (black currants, lingonberries and bilberries) for 8 weeks. Twenty subjects consuming their habitual diets served as controls. Fasting blood samples were obtained 2 weeks prior to the study, at baseline, and at 2, 4 and 8 weeks. Intake of quercetin was assessed from 3 day food records collected at baseline and at 8 weeks.

resultsThe serum quercetin concentrations were significantly higher in the subjects consuming berries compared to the control group (P=0.039 ANCOVA with repeated measures). During the berry consumption period the mean serum concentrations of quercetin ranged between 21.4 and 25.3 micro g/l in the berry group, which was 32-51% higher compared with the control group. According to 3 day food records, there was no difference in quercetin intake at baseline, but at 8 weeks the intake was 12.3+/-1.4 mg/day (mean+/-s.e.m.) in the berry group and 5.8+/-0.6 mg/day in the control group (P=0.001).

conclusionsThe results indicate that the berries used in this study are a good source of bioavailable quercetin.

Indexed as

RibesVaccinium myrtillusVaccinium vitis-idaeaAnalysis of VarianceBiological AvailabilityHumansIntestinal AbsorptionMaleMiddle AgedQuercetinQuercetin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.