ArticleBioTechniques2003
Silver particles enhance emission of fluorescent DNA oligomers.
Article in BioTechniques, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence.Molecular biology of the cell · 2023Article
- Silver Nanoparticles: Synthesis and Application for Nanomedicine.International journal of molecular sciences · 2019Review
- Upconversion in NaYF(4):Yb, Er nanoparticles amplified by metal nanostructures.Nanotechnology · 2011Article
- Enhanced fluorescence of Cy5-labeled oligonucleotides near silver island films: a distance effect study using single molecule spectroscopy.The journal of physical chemistry. B · 2006Article
- Enhanced fluorescence of Cy5-labeled DNA tethered to silver island films: fluorescence images and time-resolved studies using single-molecule spectroscopy.Analytical chemistry · 2006Article
- Metal-enhanced fluorescence: an emerging tool in biotechnology.Current opinion in biotechnology · 2005Review
- Article
- Advances in surface-enhanced fluorescence.Journal of fluorescence · 2004Review
- Radiative decay engineering 3. Surface plasmon-coupled directional emission.Analytical biochemistry · 2004Article
- Increased intensities of YOYO-1-labeled DNA oligomers near silver particles.Photochemistry and photobiology · 2003Article
- Effects of fluorophore-to-silver distance on the emission of cyanine-dye-labeled oligonucleotides.Analytical biochemistry · 2003Article
- Increased Sensitivity of Fluorescence Detection Using Metallic Nanoparticles.Pharmagenomics · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Here we describe a new opportunity in methodology for increasing the detectability of fluorescently labeled DNA on solid substrates. We show that the use of glass substrates coated with metallic silver particles results in an approximate 5-fold increase in the intensity of Cy3- or Cy5-labeled DNA oligomers. Proximity to these silver particles also increases the photostability of Cy3- and Cy5-labeled oligomers. These results suggest the use of DNA array substrates with silver particles for increased sensitivity in genetic analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.