ArticleDie Naturwissenschaften2003
Effect of prenatal exposure to hydroxyprogesterone on steroidogenic enzymes in male rats.
Article in Die Naturwissenschaften, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 16 citations in OpenAlex.
- In utero exposure to 17α-hydroxyprogesterone caproate and risk of cancer in offspring.American journal of obstetrics and gynecology · 2022Article
- Gestational Exposure to Synthetic Steroid Hormones Impaired Sperm Quantity and Quality in Wistar Rats.International journal of endocrinology · 2020Article
- Article
- Gestational exposure to hydroxyprogesterone caproate suppresses reproductive potential in male rats.Die Naturwissenschaften · 2005Article
- Impairment of male reproduction in adult rats exposed to hydroxyprogesterone caproate in utero.Die Naturwissenschaften · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnant Wistar strain albino rats were administered hydroxyprogesterone and the steroidogenic potential of the testis was analysed in the next generation adult male rats. In utero exposure to supranormal levels (10 mg/kg body weight or 25 mg/kg body weight) of hydroxyprogesterone decreased the activity levels of marker steroidogenic enzymes (3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase) of adult (mature) rat testis. Hydroxyprogesterone mediation in the suppression of rat testicular steroidogenesis is suggested, which can be correlated to the observed decrease in male reproductive potential in mammals exposed to female hormones during embryonic development.
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Registered trials
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