Inhibition of T cell function during malaria: implications for immunology and vaccinology.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed, 52 citations in OpenAlex.

1. The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum.Journal of immunology (Baltimore, Md. : 1950) · 2007
   Trial
2. Overview of the host immune response toJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
   Review
3. Regulatory T cell memory: implications for malaria.Journal of immunology (Baltimore, Md. : 1950) · 2025
   Review
4. Red pulp macrophages clear parasites, while marginal metallophilic and marginal zone macrophages support CD4Frontiers in immunology · 2025
   Article
5. The ability of Interleukin-10 to negate haemozoin-related pro-inflammatory effects has the potential to restore impaired macrophage function associated with malaria infection.Malaria journal · 2023
   Article
6. The role of different components of the immune system against Plasmodium falciparum malaria: Possible contribution towards malaria vaccine development.Molecular and biochemical parasitology · 2021
   Review
7. Hemozoin inhibition and control of clinical malaria.Advances in pharmacological sciences · 2014
   Review
8. Plasmodium vivax pre-erythrocytic-stage antigen discovery: exploiting naturally acquired humoral responses.The American journal of tropical medicine and hygiene · 2012
   Article
9. Characterization of peripheral blood T lymphocyte subsets in Chinese rhesus macaques with repeated or long-term infection with Plasmodium cynomolgi.Parasitology research · 2012
   Article
10. P. falciparum enhances HIV replication in an experimental malaria challenge system.PloS one · 2012
    Article
11. Plasmodium falciparum-infected erythrocytes and beta-hematin induce partial maturation of human dendritic cells and increase their migratory ability in response to lymphoid chemokines.Infection and immunity · 2011
    Article
12. Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system.PloS one · 2009
    Article
13. Temporal stability of naturally acquired immunity to Merozoite Surface Protein-1 in Kenyan adults.Malaria journal · 2009
    Article
14. Reduced CD3/TCR complex expression leads to immunosuppression during Plasmodium falciparum malaria.Parasitology research · 2009
    Article
15. Ex vivo monitoring of antigen-specific CD4+ T cells after recall immunization with tetanus toxoid.Clinical and vaccine immunology : CVI · 2007
    Article
16. Variable var transition rates underlie antigenic variation in malaria.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article

Corrections and comments

• Comment on
  Malaria blood stage suppression of liver stage immunity by dendritic cells.2003

Authors and funding

2 authors at 1 institution in 1 country.

Funding

Abstract

PubMed holds no abstract for this paper.

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