Evidence map›Paper›PMID 12535446›Full record

SynthesisThe Cochrane database of systematic reviews2003

Pet allergen control measures for allergic asthma in children and adults.

S Kilburn, T J Lasserson, M McKean

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Interventions for managing asthma in pregnancy.The Cochrane database of systematic reviews · 2014
    Pooled it
  4. Pooled it
  5. Review
  6. Asthma epidemiology and risk factors.Seminars in immunopathology · 2020
    Review
  7. Review
  8. Article
  9. Review
  10. INTEGRATING HEALTH INTO BUILDINGS OF THE FUTURE.Journal of solar energy engineering · 2016
    Article
  11. Article
  12. Environmental assessment and exposure control: a practice parameter--furry animals.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2012
    Article
  13. Article
  14. Review
  15. Article
  16. Diagnosis of asthma in children.BMJ (Clinical research ed.) · 2007
    Review
  17. Montelukast in the management of allergic rhinitis.Therapeutics and clinical risk management · 2007
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

S KilburnSchool of Postgraduate Medicine, University of Portsmouth, Gloucester House, Queen Alexandra Hospital, Cosham, Hants, UK, PO6 3LY. sally.kilburn@port.ac.uk
T J Lasserson
M McKean
Royal Victoria Infirmary · GBSt George's, University of London · GBUniversity of Portsmouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough pet removal has been recommended in guidelines on the management of allergic asthma, pet ownership remains high in families where one or more members have an allergy to pet dander. Allergen control measures such as air filtration units placed in the homes of pet-allergic asthmatics have been used as a means of reducing allergen exposure.

objectivesTo determine the clinical efficacy of pet allergen control measures in the homes of people with pet-allergic asthma. SEARCH STRATEGY: An electronic search of the Cochrane Controlled Trials Register was carried out. No restriction was placed on language of publication. SELECTION CRITERIA: Randomised controlled trials comparing an active allergen reduction measure with control were considered for analysis. Participants had stable pet-allergic asthma. DATA COLLECTION AND ANALYSIS: 34 references were identified by electronic searching, but only three appeared suitable for potential inclusion in the review. Two met the inclusion criteria for the analysis. Both examined the effectiveness of air filtration units. Two reviewers extracted data independently. A limited amount of data were usable for a meta-analysis. MAIN

resultsBoth trials were small (n=22 and n=35). No significant differences were detected between active intervention and control on the primary and secondary outcome measures reported in the studies. Data on absence from school or work were not reported in either study. No meta-analysis could be performed due to lack of common outcomes. REVIEWER'S

conclusionsThe available trials are too small to provide evidence for or against the use of airfiltration units to reduce allergen levels in the management of pet-allergic asthma. Adequately powered trials are needed. There are no trials of other allergen reduction measures, such as pet washing or possibly pet removal.

Indexed as

Animals, DomesticHousingAdultAir Pollution, IndoorAllergensAnimalsAsthmaChildEnvironment, ControlledFiltrationHumansRandomized Controlled Trials as TopicAllergens

Identifiers

PMID12535446
PMCPMC8689577
OpenAlexW1487672010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.