Evidence map›Paper›PMID 12532470›Full record

Trial reportWorld journal of gastroenterology2003

Effects of time interval for hemofiltration on the prognosis of severe acute pancreatitis.

En-Qiang Mao, Yao-Qing Tang, Sheng-Dao Zhang

Open access · hybridAbstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in World journal of gastroenterology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Intensive management of severe acute pancreatitis.Annals of translational medicine · 2019
    Review
  4. Observational
  5. Fluid resuscitation in acute pancreatitis.World journal of gastroenterology · 2014
    Review
  6. Article
  7. Conservative approach in the management of severe acute pancreatitis: eight-year experience in a single institution.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2008
    Article
  8. Article
  9. Continuous veno-venous haemofiltration in the treatment of severe acute pancreatitis: 6-year experience.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2007
    Article
  10. Organ failure associated with severe acute pancreatitis.World journal of gastroenterology · 2003
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

En-Qiang MaoDepartment of Surgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China. maoeq@yeah.net
Yao-Qing Tang
Sheng-Dao Zhang
Ruijin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the impact of time interval for hemofiltration (HF) on the prognosis of severe acute pancreatitis (SAP).

methodsThirty-six consecutive patients with severe acute pancreatitis were included in the study. Atlanta classification system was applied for stratification. They were randomly divided into short veno-venous HF group, (SVVH, Group 1, 20 patients); and long veno-venous HF group (LVVH, Group 2, 16 patients). In group 1, SVVH was stopped when the abdominal signs disappeared, and heart rate and breath rate were less than 90 beats/min and 20 times/min, respectively. HF was stopped if SVVH was continued, and when heart rate and breath rate were more than 90 beats/min and 20 times/min again (Group 2). Except that the time interval for HF was different, other parameters for HF were the same. And conservative curing rate, survival rate, cost for hospital stay and length of hospital stay were observed.

resultsTime interval for HF in Group 1 (3.81+/-1.3 hr) was shorter than that of in Group 2 (9.38+/-2.9 hr), P<0.01. Conservative curing rate (90 %) in Group 1 was much higher than that in Group 2 (56.3 %) (P<0.05); but cost in Group 1 (RMB 56 600+/-56 400 Yuan) was lower than that in Group 2 (RMB 137 000+/-105 000 Yuan) (P<0.05). And the survival rate (95 %) in Group 1 was higher than that in Group 2 (81.3 %) (P<0.25); however, hospital stay in Group 1 (44.3+/-41 days) was shorter than that in Group 2 (55.2+/-39.5 days) (P<0.2). So, the prognosis was not improved through the prolongation of time interval for HF, but side-effects were seen.

conclusionThe prognosis was not further improved by LVVH in the treatment of SAP, with side-effects. Time interval for HF plays an important role in treatment of SAP in early stage. SVVH is thought to be superior to LVVH; and LVVH is superior to CVVH in early (72 hrs) treatment of SAP.

Indexed as

HemofiltrationAcute DiseaseAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPancreatitisPrognosisSeverity of Illness IndexTime Factors

Identifiers

PMID12532470
PMCPMC4611350
OpenAlexW2397192727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.