ArticleGenome research2003
Pericentromeric duplications in the laboratory mouse.
Article in Genome research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Mathematical model for the role of multiple pericentromeric repeats on heterochromatin assembly.PLoS computational biology · 2024Article
- Physical Mapping of Amplified Copies of the 5-Enolpyruvylshikimate-3-Phosphate Synthase Gene in Glyphosate-Resistant Amaranthus tuberculatus.Plant physiology · 2017Article
- Evolution of the structure and composition of house mouse satellite DNA sequences in the subgenus Mus (Rodentia: Muridea): a cytogenomic approach.Chromosoma · 2013Article
- Unstable transmission of rice chromosomes without functional centromeric repeats in asexual propagation.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2009Article
- Comparative genomics and molecular dynamics of DNA repeats in eukaryotes.Microbiology and molecular biology reviews : MMBR · 2008Review
- Comparative sequence analyses reveal sites of ancestral chromosomal fusions in the Indian muntjac genome.Genome biology · 2008Article
- Phylogenomics of the genus Mus (Rodentia; Muridae): extensive genome repatterning is not restricted to the house mouse.Proceedings. Biological sciences · 2006Article
- Dynamic evolution at pericentromeres.Genome research · 2006Article
- The rice nuclear genome continuously integrates, shuffles, and eliminates the chloroplast genome to cause chloroplast-nuclear DNA flux.The Plant cell · 2005Article
- Mapping segmental and sequence variations among laboratory mice using BAC array CGH.Genome research · 2005Article
- The feline major histocompatibility complex is rearranged by an inversion with a breakpoint in the distal class I region.Immunogenetics · 2005Article
- Human, mouse, and rat genome large-scale rearrangements: stability versus speciation.Genome research · 2004Article
- Analysis of segmental duplications and genome assembly in the mouse.Genome research · 2004Article
- Article
- Recent segmental duplications in the working draft assembly of the brown Norway rat.Genome research · 2004Article
- Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments.The EMBO journal · 2004Article
- Comparative sequence analysis of a single-gene conserved segment in mouse and human.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Duplications have long been postulated to be an important mechanism by which genomes evolve. Interspecies genomic comparisons are one method by which the origin and molecular mechanism of duplications can be inferred. By comparative mapping in human, mouse, and rat, we previously found evidence for a recent chromosome-fission event that occurred in the mouse lineage. Cytogenetic mapping revealed that the genomic segments flanking the fission site appeared to be duplicated, with copies residing near the centromere of multiple mouse chromosomes. Here we report the mapping and sequencing of the regions of mouse chromosomes 5 and 6 involved in this chromosome-fission event as well as the results of comparative sequence analysis with the orthologous human and rat genomic regions. Our data indicate that the duplications associated with mouse chromosomes 5 and 6 are recent and that the resulting duplicated segments share significant sequence similarity with a series of regions near the centromeres of the mouse chromosomes previously identified by cytogenetic mapping. We also identified pericentromeric duplicated segments shared between mouse chromosomes 5 and 1. Finally, novel mouse satellite sequences as well as putative chimeric transcripts were found to be associated with the duplicated segments. Together, these findings demonstrate that pericentromeric duplications are not restricted to primates and may be a common mechanism for genome evolution in mammals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.