ArticleJournal of virology2003
Duck hepatitis B virus virion secretion requires a double-stranded DNA genome.
Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 47 citations in OpenAlex.
- New Biomarkers of Chronic Hepatitis B.Gut and liver · 2019Review
- Extracellular Hepatitis B Virus RNAs Are Heterogeneous in Length and Circulate as Capsid-Antibody Complexes in Addition to Virions in Chronic Hepatitis B Patients.Journal of virology · 2018Article
- Host functions used by hepatitis B virus to complete its life cycle: Implications for developing host-targeting agents to treat chronic hepatitis B.Antiviral research · 2018Review
- Common and Distinct Capsid and Surface Protein Requirements for Secretion of Complete and Genome-Free Hepatitis B Virions.Journal of virology · 2018Article
- The immunological function of extracellular vesicles in hepatitis B virus-infected hepatocytes.PloS one · 2018Article
- Capsid Phosphorylation State and Hepadnavirus Virion Secretion.Journal of virology · 2017Article
- Complete and Incomplete Hepatitis B Virus Particles: Formation, Function, and Application.Viruses · 2017Review
- Assembly and Release of Hepatitis B Virus.Cold Spring Harbor perspectives in medicine · 2015Review
- Hepadnavirus Genome Replication and Persistence.Cold Spring Harbor perspectives in medicine · 2015Review
- Genome-free hepatitis B virion levels in patient sera as a potential marker to monitor response to antiviral therapy.Journal of viral hepatitis · 2015Article
- Regulation of multiple stages of hepadnavirus replication by the carboxyl-terminal domain of viral core protein in trans.Journal of virology · 2015Article
- Snow goose hepatitis B virus (SGHBV) envelope and capsid proteins independently contribute to the ability of SGHBV to package capsids containing single-stranded DNA in virions.Journal of virology · 2014Article
- Maturation-associated destabilization of hepatitis B virus nucleocapsid.Journal of virology · 2013Article
- Host factors involved in hepatitis B virus maturation, assembly, and egress.Medical microbiology and immunology · 2012Review
- Secretion of genome-free hepatitis B virus--single strand blocking model for virion morphogenesis of para-retrovirus.PLoS pathogens · 2011Article
- Alix regulates egress of hepatitis B virus naked capsid particles in an ESCRT-independent manner.Cellular microbiology · 2011Article
- HBV life cycle: entry and morphogenesis.Viruses · 2009Article
- Molecular virology of hepatitis B virus for clinicians.Clinics in liver disease · 2007Review
- Involvement of host cellular multivesicular body functions in hepatitis B virus budding.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Formation of hepatitis B virus covalently closed circular DNA: removal of genome-linked protein.Journal of virology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Hepatitis B virus assembly begins with the packaging of an RNA pregenome into intracellular nucleocapsids, with subsequent reverse transcription within these nucleocapsids converting the RNA into a characteristic, partially double-stranded DNA, which, alone, is found in enveloped extracellular virions as the viral genome. Using a synchronized replication system for the duck hepatitis B virus, together with a stringent two-step assay for virion secretion, we demonstrate that this selective genome secretion results from an intrinsic secretion competence gained only by the nucleocapsids at the late stage of reverse transcription.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.