Evidence map›Paper›PMID 12525661›Full record

ArticleJournal of virology2003

Frequency and phenotype of circulating Valpha24/Vbeta11 double-positive natural killer T cells during hepatitis C virus infection.

Michaela Lucas, Stephan Gadola, Ute Meier, Neil T Young, Gillian Harcourt, Anastasios Karadimitris, Nikki Coumi, Dave Brown, Geoff Dusheiko, Vincenzo Cerundolo and 1 more

Abstract read
In one paragraph

Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. The Liver and the Hepatic Immune Response inPathogens (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. NKT cells in liver diseases.Frontiers of medicine · 2018
    Review
  14. Article
  15. Immunopathogenesis of Hepatitis C Virus Infection.Gastroenterology clinics of North America · 2015
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michaela LucasPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.
Stephan Gadola
Ute Meier
Neil T Young
Gillian Harcourt
Anastasios Karadimitris
Nikki Coumi
Dave Brown
Geoff Dusheiko
Vincenzo Cerundolo
Paul Klenerman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer T (NKT) cells are thought to be involved in innate responses against infection. We investigated one specific type of NKT cell, Valpha24/Vbeta11 double positive, in hepatitis C virus (HCV) infection. Lower frequencies of this population were detected in the blood of HCV PCR-positive patients than in controls. Unlike Valpha24/Vbeta11 NKT cells found in blood, those in the liver appeared to be recently activated.

Indexed as

Antigens, CDAntigens, Differentiation, T-LymphocyteCD3 ComplexCD56 AntigenCD69 AntigensHepatitis CHumansImmunophenotypingKiller Cells, NaturalLectins, C-TypeLymphocyte ActivationReceptors, Antigen, T-Cell, alpha-betaT-Lymphocyte SubsetsAntigens, CDAntigens, Differentiation, T-LymphocyteCD3 ComplexCD56 AntigenCD69 AntigensLectins, C-TypeReceptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID12525661
PMCPMC140901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.