ArticleJournal of virology2003
Enhancer-like activity of a brome mosaic virus RNA promoter.
Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Review
- A balance between circular and linear forms of the dengue virus genome is crucial for viral replication.RNA (New York, N.Y.) · 2010Article
- RNA binding by the brome mosaic virus capsid protein and the regulation of viral RNA accumulation.Journal of molecular biology · 2009Article
- Long-distance RNA-RNA interactions between terminal elements and the same subset of internal elements on the potato virus X genome mediate minus- and plus-strand RNA synthesis.RNA (New York, N.Y.) · 2007Article
- A 5' RNA element promotes dengue virus RNA synthesis on a circular genome.Genes & development · 2006Article
- Mechanism of stimulation of plus-strand synthesis by an RNA replication enhancer in a tombusvirus.Journal of virology · 2005Article
- Mutual interference between genomic RNA replication and subgenomic mRNA transcription in brome mosaic virus.Journal of virology · 2005Article
- Short internal sequences involved in replication and virion accumulation in a subviral RNA of turnip crinkle virus.Journal of virology · 2005Article
- The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor.Journal of virology · 2004Article
- cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genome.Journal of virology · 2004Article
- Dissecting the requirement for subgenomic promoter sequences by RNA recombination of brome mosaic virus in vivo: evidence for functional separation of transcription and recombination.Journal of virology · 2004Article
- Repression and derepression of minus-strand synthesis in a plus-strand RNA virus replicon.Journal of virology · 2004Article
- Requirements for brome mosaic virus subgenomic RNA synthesis in vivo and replicase-core promoter interactions in vitro.Journal of virology · 2004Article
- A replication silencer element in a plus-strand RNA virus.The EMBO journal · 2003Article
- Fitness of a turnip crinkle virus satellite RNA correlates with a sequence-nonspecific hairpin and flanking sequences that enhance replication and repress the accumulation of virions.Journal of virology · 2003Article
- A transcriptionally active subgenomic promoter supports homologous crossovers in a plus-strand RNA virus.Journal of virology · 2003Article
- Stable RNA structures can repress RNA synthesis in vitro by the brome mosaic virus replicase.RNA (New York, N.Y.) · 2003Article
- Brome mosaic virus RNA syntheses in vitro and in barley protoplasts.Journal of virology · 2003Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As with transcription from DNA templates, RNA synthesis from viral RNA templates must initiate accurately. RNA sequences named specificity and initiation determinants allow recognition of and coordinated interaction with the viral replication enzyme. Using enriched replicase from brome mosaic virus (BMV)-infected plants and variants of the promoter template for minus-strand and subgenomic RNA initiation, we found that a specificity determinant for minus-strand initiation could function at variable distances and positions from the 3' initiation site in a manner similar to enhancers of transcription from DNA templates. This determinant's addition could convert a cellular tRNA into a template for RNA synthesis by the BMV replicase in vitro. Furthermore, the same specificity element could direct internal initiation, which occurred at a highly preferred site in a manner distinct from initiation at the 3' terminus of the template. These results document two distinct modes of initiation site recognition by a viral RNA replicase.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.