Evidence map›Paper›PMID 12521563›Full record

ArticleCurrent treatment options in neurology2003

Current Complementary and Alternative Therapies for Multiple Sclerosis.

Allen C. Bowling, Thomas M. Stewart

Abstract read
PubMed Publisher
In one paragraph

Article in Current treatment options in neurology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
10.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Dietary interventions for multiple sclerosis-related outcomes.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Article
  4. Uses of complementary and alternative medicine in multiple sclerosis.Journal of traditional and complementary medicine · 2014
    Review
  5. Review
  6. Article
  7. Complementary and alternative medicine in patients with chronic lymphocytic leukemia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2009
    Article
  8. Article
  9. Review
  10. [Diet and multiple sclerosis].Der Nervenarzt · 2005
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Allen C. BowlingComplementary and Alternative Medicine Program, Rocky Mountain Multiple Sclerosis Center, 701 East Hampden Avenue, #530, Englewood, CO 80110, USA. bowling@mscenter.org
Thomas M. Stewart
Rocky Mountain MS Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of complementary and alternative medicine (CAM) appears to be high in the general population and in patients with multiple sclerosis (MS). There are no diets or dietary supplements that are definitely effective in altering the disease course in MS. However, diets and dietary supplements that increase the intake of polyunsaturated fatty acids may produce mildly beneficial effects. Because these approaches are not definitely effective, they may be of limited interest to physicians and other conventional health providers. In contrast, for patients with MS, these interventions may be of considerable interest, because they may be mildly effective and are inexpensive and relatively safe. Vitamin D, ginkgo biloba, cannabinoids, and Padma 28 produce immunomodulatory actions and therapeutic effects in experimental autoimmune encephalomyelitis. However, for these compounds, there are not enough clinical trial data or safety information to support their use as disease-modifying therapies. The role of antioxidant compounds in MS is unclear. There is no evidence that vitamin B(12) supplementation or gluten-free diets are effective MS therapies. Conventional health providers can play an important role in the care of MS patients by being open to discuss CAM therapies and by providing objective MS-relevant CAM information.

Identifiers

PMID12521563
OpenAlexW2067791971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.