ReviewLancet (London, England)2003
The common cold.
Review in Lancet (London, England), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 434 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Healsea® Hypertonic Nasal Spray 2.7% in the Treatment of Acute Infectious Rhinitis in Adults
Efficacy and Safety of Healsea® Babykids in the Treatment of Acute Infectious Rhinitis Symptoms in Children
Efficacy and Safety of Ibuprofen/Loratadine Fixed-dose Combination Versus the Fixed-dose Administration of Monotherapy as Symptomatic Treatment for Patients With the Common Cold
Who cites it
434 citing papers in PubMed, 12 syntheses or guidelines pooled it, 1,046 citations in OpenAlex.
- A systematic review and meta-analysis on diagnostic accuracy of point-of-care C-reactive protein devices for acute respiratory tract infections.Infection · 2026Pooled it
- Global meta-analysis of short-term associations between ambient temperature and pathogen-specific respiratory infections, 2004 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Pooled it
- Pooled it
- Pediatric efficacy and safety in common cold treated with herbal medicine (PEACH): a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Vaccines for the common cold.The Cochrane database of systematic reviews · 2022Pooled it
- Oral antihistamine-decongestant-analgesic combinations for the common cold.The Cochrane database of systematic reviews · 2022Pooled it
- Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis.European journal of nutrition · 2021Pooled it
- Preventive effects of tea and tea catechins against influenza and acute upper respiratory tract infections: a systematic review and meta-analysis.European journal of nutrition · 2021Pooled it
- Effect of probiotic fermented dairy products on incidence of respiratory tract infections: a systematic review and meta-analysis of randomized clinical trials.Nutrition journal · 2021Pooled it
- Role of Probiotics in Stimulating the Immune System in Viral Respiratory Tract Infections: A Narrative Review.Nutrients · 2020Pooled it
- Eunkyosan for the common cold: A PRISMA-compliment systematic review of randomised, controlled trials.Medicine · 2020Pooled it
- Rinse-free hand wash for reducing absenteeism among preschool and school children.The Cochrane database of systematic reviews · 2020Pooled it
- Efficacy and safety of AtusinBMC pulmonary medicine · 2025Trial
- Trial
- Patient perceptions of primary care rapid respiratory microbiological point-of-care testing: a qualitative study.BMJ open · 2025Trial
- Rapid microbiological respiratory point-of-care testing: a qualitative study with primary care clinicians.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Trial
- Docosahexaenoic Acid Supplementation During Pregnancy and Lactation and Infant Morbidity: Findings from DHANI Trial.Indian pediatrics · 2025Trial
- ColdZyme® reduces viral load and upper respiratory tract infection duration and protects airway epithelia from infection with human rhinoviruses.The Journal of physiology · 2025Trial
- Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial.Pediatric research · 2024Trial
- Effects of Vitamin D Supplementation and Baseline Vitamin D Status on Acute Respiratory Infections and Cathelicidin: A Randomized Controlled Trial.Open forum infectious diseases · 2024Trial
374 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite great advances in medicine, the common cold continues to be a great burden on society in terms of human suffering and economic losses. Of the several viruses that cause the disease, the role of rhinoviruses is most prominent. About a quarter of all colds are still without proven cause, and the recent discovery of human metapneumovirus suggests that other viruses could remain undiscovered. Research into the inflammatory mechanisms of the common cold has elucidated the complexity of the virus-host relation. Increasing evidence is also available for the central role of viruses in predisposing to complications. New antivirals for the treatment of colds are being developed, but optimum use of these agents would require rapid detection of the specific virus causing the infection. Although vaccines against many respiratory viruses could also become available, the ultimate prevention of the common cold seems to remain a distant aim.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.