Evidence map›Paper›PMID 12511716›Full record

Trial reportThorax2003

Self-management of asthma in general practice, asthma control and quality of life: a randomised controlled trial.

B P A Thoonen, T R J Schermer, G Van Den Boom, J Molema, H Folgering, R P Akkermans, R Grol, C Van Weel, C P Van Schayck

Abstract readClinical TrialMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Thorax, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Personalised asthma action plans for adults with asthma.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Chronic disease management programmes for adults with asthma.The Cochrane database of systematic reviews · 2015
    Pooled it
  3. Digital asthma self-management interventions: a systematic review.Journal of medical Internet research · 2014
    Pooled it
  4. Pooled it
  5. Summary of recommendations from the Canadian Asthma Consensus guidelines, 2003.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2005
    Guideline
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  7. Trial
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  9. House dust mite allergen avoidance and self-management in allergic patients with asthma: randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2007
    Trial
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  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

B P A ThoonenDepartment of General Practice/Family Medicine, University Medical Centre Nijmegen, The Netherlands. b.thoonen@hag.umcn.nl
T R J Schermer
G Van Den Boom
J Molema
H Folgering
R P Akkermans
R Grol
C Van Weel
C P Van Schayck

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA study was undertaken to determine the effectiveness of asthma self-management in general practice.

methodsNineteen general practices were randomly allocated to usual care (UC) or self-management (SM). Asthma patients were included after confirmation of the GP diagnosis. Follow up was 2 years. Patients kept diary cards and visited the lung function laboratory every 6 months. Outcomes were number of successfully treated weeks, limited activity days, asthma specific quality of life, forced expiratory volume in 1 second (FEV(1)), FEV(1) reversibility, concentration of histamine provoking a fall in FEV(1) of 20% or more (PC(20) histamine), and amount of inhaled steroids.

resultsA total of 214 patients were included in the study (104 UC/110 SM; one third of the total asthma population in general practice); 62% were female. The mean percentage of successfully treated weeks per patient in the UC group was 72% (74/103 weeks) compared with 78% (81/105 weeks) in the SM group (p=0.003). The mean number of limited activity days was 1.2 (95% CI 0.5 to 1.9) in the SM group and 3.9 (95% CI 2.5 to 5.4) in the UC group. The estimated increase in asthma quality of life score was 0.10 points per visit in the UC group and 0.21 points per visit in the SM group (p=0.055). FEV(1), FEV(1) reversibility, and PC(20) histamine did not change. There was a saving of 217 puffs of inhaled steroid per patient in favour of the SM group (p<0.05).

conclusionSelf-management lowers the burden of illness as perceived by patients with asthma and is at least as effective as the treatment usually provided in Dutch primary care. Self-management is a safe basis for intermittent treatment with inhaled corticosteroids.

Indexed as

Quality of LifeAdultAnti-Asthmatic AgentsAsthmaFamily PracticeFemaleFollow-Up StudiesForced Expiratory VolumeHumansMalePeak Expiratory Flow RateSelf CareTreatment OutcomeVital CapacityAnti-Asthmatic Agents

Identifiers

PMID12511716
PMCPMC1746452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.