ArticleJournal of bacteriology2003
Novel methylotrophy genes of Methylobacterium extorquens AM1 identified by using transposon mutagenesis including a putative dihydromethanopterin reductase.
Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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Who cites it
31 citing papers in PubMed.
- CRISPRi-based functional genomic screening identifies genes essential for CHScience advances · 2026Article
- Lanthanide-dependent isolation of phyllosphere methylotrophs selects for a phylogenetically conserved but metabolically diverse community.bioRxiv : the preprint server for biology · 2025Article
- Identification and characterization of a small-molecule metallophore involved in lanthanide metabolism.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Heterologous production of 3-hydroxypropionic acid in Methylorubrum extorquens by introducing the mcr gene via a multi-round chromosomal integration system based on cre-lox71/lox66 and transposon.Microbial cell factories · 2024Article
- Biosynthesis of L-5-methyltetrahydrofolate by genetically engineered Escherichia coli.Microbial biotechnology · 2022Article
- Gene products and processes contributing to lanthanide homeostasis and methanol metabolism in Methylorubrum extorquens AM1.Scientific reports · 2020Article
- Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function.The Journal of biological chemistry · 2020Article
- Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria.Frontiers in microbiology · 2018Article
- Lanthanide-Dependent Regulation of Methanol Oxidation Systems in Methylobacterium extorquens AM1 and Their Contribution to Methanol Growth.Journal of bacteriology · 2016Article
- Wide Distribution of Genes for Tetrahydromethanopterin/Methanofuran-Linked C1 Transfer Reactions Argues for Their Presence in the Common Ancestor of Bacteria and Archaea.Frontiers in microbiology · 2016Article
- Discovery and characterization of the first archaeal dihydromethanopterin reductase, an iron-sulfur flavoprotein from Methanosarcina mazei.Journal of bacteriology · 2014Article
- Genetic and phenotypic comparison of facultative methylotrophy between Methylobacterium extorquens strains PA1 and AM1.PloS one · 2014Article
- A novel pair of inducible expression vectors for use in Methylobacterium extorquens.BMC research notes · 2013Article
- Recovering from a bad start: rapid adaptation and tradeoffs to growth below a threshold density.BMC evolutionary biology · 2012Article
- Alternative route for glyoxylate consumption during growth on two-carbon compounds by Methylobacterium extorquens AM1.Journal of bacteriology · 2010Article
- Article
- Bestowing inducibility on the cloned methanol dehydrogenase promoter (PmxaF) of Methylobacterium extorquens by applying regulatory elements of Pseudomonas putida F1.Applied and environmental microbiology · 2006Article
- Multicopy integration and expression of heterologous genes in Methylobacterium extorquens ATCC 55366.Applied and environmental microbiology · 2006Article
- QscR-mediated transcriptional activation of serine cycle genes in Methylobacterium extorquens AM1.Journal of bacteriology · 2005Article
- Analysis of gene islands involved in methanopterin-linked C1 transfer reactions reveals new functions and provides evolutionary insights.Journal of bacteriology · 2005Article
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Authors and funding
4 authors.
Funding
Abstract
Ten novel methylotrophy genes of the facultative methylotroph Methylobacterium extorquens AM1 were identified from a transposon mutagenesis screen. One of these genes encodes a product having identity with dihydrofolate reductase (DHFR). This mutant has a C(1)-defective and methanol-sensitive phenotype that has previously only been observed for strains defective in tetrahydromethanopterin (H(4)MPT)-dependent formaldehyde oxidation. These results suggest that this gene, dmrA, may encode dihydromethanopterin reductase, an activity analogous to that of DHFR that is required for the final step of H(4)MPT biosynthesis.
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