Evidence map›Paper›PMID 12511513›Full record

ArticleJournal of bacteriology2003

Formation of an F' plasmid by recombination between imperfectly repeated chromosomal Rep sequences: a closer look at an old friend (F'(128) pro lac).

Eric Kofoid, Ulfar Bergthorsson, E Susan Slechta, John R Roth

Abstract read
In one paragraph

Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Synonymous Mutations inFrontiers in microbiology · 2020
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Stress-Induced Mutagenesis.EcoSal Plus · 2012
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Multiple pathways of selected gene amplification during adaptive mutation.Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eric KofoidDepartment of Biology, University of Utah, Salt Lake City 84122, USA.
Ulfar Bergthorsson
E Susan Slechta
John R Roth

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmid F'(128) was formed by an exchange between chromosomal Rep sequences that placed lac near dinB between many pairs of Rep sequences. Plasmid F'(128) is critical for selection-enhanced lac reversion (adaptive mutation), which requires prior lac amplification. The structure of F'(128) supports the idea that amplification is initiated by Rep-Rep recombination and that general mutagenesis requires coamplification of dinB (error-prone polymerase) with lac.

Indexed as

Recombination, GeneticAdenosine TriphosphatasesBase SequenceChromosomes, BacterialDNA HelicasesEscherichia coliEscherichia coli ProteinsF FactorLac OperonMolecular Sequence DataMutationRepetitive Sequences, Nucleic AcidAdenosine TriphosphatasesDNA HelicasesEscherichia coli Proteinsrep protein, E coli

Identifiers

PMID12511513
PMCPMC145332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.