ArticleNature2003
The DNA sequence and analysis of human chromosome 14.
Article in Nature, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- VIPAS39 related arthrogryposis-renal dysfunction-cholestasis syndrome-case report and systematic review.Orphanet journal of rare diseases · 2024Pooled it
- The Cellular Transcriptome in the Maternal Circulation During Normal Pregnancy: A Longitudinal Study.Frontiers in immunology · 2019Trial
- The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications.International journal of molecular sciences · 2024Review
- Decreased DIO3OS Expression Predicts Poor Prognosis in Hepatocellular Carcinoma and is Associated with Immune Infiltration.Biochemical genetics · 2023Article
- CHOmpact: A reduced metabolic model of Chinese hamster ovary cells with enhanced interpretability.Biotechnology and bioengineering · 2023Article
- Organization and Complexity of the Yak (Bos Grunniens) Immunoglobulin Loci.Frontiers in immunology · 2022Article
- Review
- Taxonomy of Mitochondrial Cytochrome B Proteins of the Same Amino Acid Sequence Length.TheScientificWorldJournal · 2021Article
- Induction of the apoptotic pathway by oxidative stress in spontaneous preterm birth: Single nucleotide polymorphisms, maternal lifestyle factors and health status.Biomedical reports · 2018Article
- SFTA3 - a novel surfactant protein of the ocular surface and its role in corneal wound healing and tear film surface tension.Scientific reports · 2018Article
- Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH).Diagnostic pathology · 2017Article
- Understanding specific functions of PARP-2: new lessons for cancer therapy.American journal of cancer research · 2016Review
- Novel exons and splice variants in the human antibody heavy chain identified by single cell and single molecule sequencing.PloS one · 2015Article
- Protein modeling and molecular dynamics simulation of the two novel surfactant proteins SP-G and SP-H.Journal of molecular modeling · 2014Article
- Chromosome duplication (14q) and the genotype phenotype correlation.International journal of fertility & sterility · 2014Article
- IgG subclasses and allotypes: from structure to effector functions.Frontiers in immunology · 2014Review
- Interstitial 14q24.3 to q31.3 deletion in a 6-year-old boy with a non-specific dysmorphic phenotype.Molecular cytogenetics · 2014Article
- Distinct retroelement classes define evolutionary breakpoints demarcating sites of evolutionary novelty.BMC genomics · 2009Article
- Recombinant chromosome 14 due to maternal pericentric inversion.Journal of applied genetics · 2008Article
- ADAM15 gene structure and differential alternative exon use in human tissues.BMC molecular biology · 2007Article
Corrections and comments
- Erratum issued
Authors and funding
99 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromosome 14 is one of five acrocentric chromosomes in the human genome. These chromosomes are characterized by a heterochromatic short arm that contains essentially ribosomal RNA genes, and a euchromatic long arm in which most, if not all, of the protein-coding genes are located. The finished sequence of human chromosome 14 comprises 87,410,661 base pairs, representing 100% of its euchromatic portion, in a single continuous segment covering the entire long arm with no gaps. Two loci of crucial importance for the immune system, as well as more than 60 disease genes, have been localized so far on chromosome 14. We identified 1,050 genes and gene fragments, and 393 pseudogenes. On the basis of comparisons with other vertebrate genomes, we estimate that more than 96% of the chromosome 14 genes have been annotated. From an analysis of the CpG island occurrences, we estimate that 70% of these annotated genes are complete at their 5' end.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.