ArticleArchives of disease in childhood2003
Relation between measurements of cough severity.
Article in Archives of disease in childhood, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Tools for assessing outcomes in studies of chronic cough: CHEST guideline and expert panel report.Chest · 2015Guideline
- Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults.The Cochrane database of systematic reviews · 2014Pooled it
- Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults.The Cochrane database of systematic reviews · 2011Pooled it
- Trial
- Trial
- Methods for assessing cough sensitivity.Journal of thoracic disease · 2020Review
- Development and construct validation of a parent-proxy quality of life instrument in children with bronchopulmonary dysplasia aged 4-8 years old.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- The objective assessment of cough frequency: accuracy of the LR102 device.Cough (London, England) · 2011Article
- A portable automatic cough analyser in the ambulatory assessment of cough.Biomedical engineering online · 2010Article
- Article
- Changes in health-related quality of life and clinical implications in Chinese patients with chronic cough.Cough (London, England) · 2009Article
- Article
- Evaluation of a new self-contained, ambulatory, objective cough monitor.Cough (London, England) · 2006Article
- Cough: are children really different to adults?Cough (London, England) · 2005Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn asthma, measurements of airway inflammation correlate poorly with clinical markers and airway hyperresponsiveness. While the relation between determinants of asthma severity is known, that for cough is unknown. We hypothesised that cough sensitivity changes relate to changes in cough scores and objectively measured cough frequency.
aimsTo examine the relation between commonly used outcome measurements of cough severity in children.
methodsThe concentration of capsaicin causing two and five or more coughs (C2 and C5 respectively), cough frequency objectively measured using an ambulatory cough meter, and parent and child recorded subjective cough scores were determined in 40 children with recurrent cough on two occasions.
resultsOn occasion one, log cough frequency significantly correlated with parent and child recorded log cough score (r(s) = 0.32, p = 0.05; and r(s) = 0.32, p = 0.046 respectively) and significantly negatively correlated with log C2 (r(s)= -0.5, p = 0.005). Subjective cough scores did not relate to either C2 or C5. On occasion two, the relation between cough frequency and C2 and C5 measures was lost, but C2 had a weak but significant relation to parent recorded cough score (r(s) = -0.38, p = 0.047). When the changes in the log values were determined, C5 but not C2 significantly related to cough frequency.
conclusionIn children, measures of cough sensitivity have a weak relation with cough frequency. Subjective cough scores have a stronger and consistent relation with cough frequency. These cough severity indices measure different aspects of cough. The choice of indices depends on the reason for performing the measurement.
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