ArticleProceedings. Biological sciences2002
Functional and ecological significance of rDNA intergenic spacer variation in a clonal organism under divergent selection for production rate.
Article in Proceedings. Biological sciences, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 95 citations in OpenAlex.
- Comparative mitochondrial genome brings insights to slight variation in gene proportion and large intergenic spacer and phylogenetic relationship of mudskipper species.Scientific reports · 2024Article
- An experimental test of the growth rate hypothesis as a predictive framework for microevolutionary adaptation.Ecology · 2023Article
- Asexuality Associated with Marked Genomic Expansion of Tandemly Repeated rRNA and Histone Genes.Molecular biology and evolution · 2021Article
- Evolutionary Diversity in the Intracellular Microsporidian Parasite Nosema sp. Infecting Wild Silkworm Revealed by IGS Nucleotide Sequence Diversity.Journal of molecular evolution · 2020Article
- Evolution without standing genetic variation: change in transgenerational plastic response under persistent predation pressure.Heredity · 2018Article
- Evolution of organismal stoichiometry in a long-term experiment withRoyal Society open science · 2017Article
- Functional constraints and evolutionary dynamics of the repeats in the rDNA internal transcribed spacer 2 of members of the Anopheles barbirostris group.Parasites & vectors · 2014Article
- Characterization of the intergenic spacer rDNAs of two pig nodule worms, Oesophagostomum dentatum and O. quadrispinulatum.TheScientificWorldJournal · 2014Article
- Nucleic acid content in crustacean zooplankton: bridging metabolic and stoichiometric predictions.PloS one · 2014Article
- The rate-size trade-off structures intraspecific variation in Daphnia ambigua life history parameters.PloS one · 2013Article
- Article
- Linking genes to communities and ecosystems: Daphnia as an ecogenomic model.Proceedings. Biological sciences · 2012Article
- Testing the growth rate hypothesis in vascular plants with above- and below-ground biomass.PloS one · 2012Article
- Reexamination of Culex pipiens hybridization zone in the Eastern United States by ribosomal DNA-based single nucleotide polymorphism markers.The American journal of tropical medicine and hygiene · 2011Article
- Looking inside the box: using Raman microspectroscopy to deconstruct microbial biomass stoichiometry one cell at a time.The ISME journal · 2011Article
- Nuclear ribosomal spacer regions in plant phylogenetics: problems and prospects.Molecular biology reports · 2010Article
- Article
- Sensitivity of Daphnia species to phosphorus-deficient diets.Oecologia · 2010Article
- High-frequency intragenomic heterogeneity of the ribosomal DNA intergenic spacer region in Trichophyton violaceum.Eukaryotic cell · 2008Article
- Stoichiometry and the new biology: the future is now.PLoS biology · 2007Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has recently been hypothesized that variation in the intergenic spacer (IGS) of rDNA has considerable developmental, evolutionary and ecological significance through effects on growth rate and body C : N : P stoichiometry resulting from the role of the IGS in production of rRNA. To test these ideas, we assessed changes in size and structure of the repetitive region of the IGS, juvenile growth rate (JGR), RNA and phosphorus (P) contents in clonal lineages of Daphnia pulex derived from a single female and subjected to divergent selection on weight-specific fecundity (WSF). As a result of selection, WSF diverged rapidly, with significant reductions within two generations. Other significant changes accompanying shifts in WSF were that juveniles produced by low-WSF females grew more rapidly and had higher RNA and P contents. An increased predominance of long IGS variants was observed in lineages with elevated JGRs and low WSF. The observed variations in IGS length were related to the number of subrepeat units carrying a promoter sequence in the repetitive region. These results strongly support the hypothesized relationships, indicate a genetic mechanism for the evolution of such associations and demonstrate that Daphnia (and perhaps other parthenogens) possess considerable potential for rapid adaptive change in major life-history traits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.