ArticleJournal of anatomy2002
Elastic fibre organization in the intervertebral discs of the bovine tail.
Article in Journal of anatomy, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 181 citations in OpenAlex.
- Diverse and multifunctional roles for perlecan (JOR spine · 2024Review
- Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review).International journal of molecular medicine · 2024Review
- Apparent diffusion coefficient and T2* mapping on 3T MRI in normal and degenerative lumbar intervertebral discs.Polish journal of radiology · 2023Article
- Extracellular matrix in intervertebral disc: basic and translational implications.Cell and tissue research · 2022Review
- Elastic Fibers in the Intervertebral Disc: From Form to Function and toward Regeneration.International journal of molecular sciences · 2022Review
- Self-Assembling Peptide Hydrogels as Functional Tools to Tackle Intervertebral Disc Degeneration.Gels (Basel, Switzerland) · 2022Review
- Differential characterization of lumbar spine associated tissue histology with nonlinear optical microscopy.Biomedical optics express · 2022Article
- Development, Pathogenesis, and Regeneration of the Intervertebral Disc: Current and Future Insights Spanning Traditional to Omics Methods.Frontiers in cell and developmental biology · 2022Review
- Biochemical and immuno-histochemical localization of type IIA procollagen in annulus fibrosus of mature bovine intervertebral disc.Matrix biology plus · 2021Article
- 3D virtual reconstruction and quantitative assessment of the human intervertebral disc's annulus fibrosus: a DTI tractography study.Scientific reports · 2021Article
- Sensitivity of Intervertebral Disc Finite Element Models to Internal Geometric and Non-geometric Parameters.Frontiers in bioengineering and biotechnology · 2021Article
- A Robust Multiscale and Multiphasic Structure-Based Modeling Framework for the Intervertebral Disc.Frontiers in bioengineering and biotechnology · 2021Article
- Functional cell phenotype induction with TGF-β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair.European cells & materials · 2020Article
- GEORG SCHMORL PRIZE OF THE GERMAN SPINE SOCIETY (DWG) 2018: combined inflammatory and mechanical stress weakens the annulus fibrosus: evidences from a loaded bovine AF organ culture.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- Shear-wave elastography can evaluate annulus fibrosus alteration in adolescent scoliosis.European radiology · 2018Article
- Biomaterials for intervertebral disc regeneration and repair.Biomaterials · 2017Review
- Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017Article
- Derivation of inter-lamellar behaviour of the intervertebral disc annulus.Journal of the mechanical behavior of biomedical materials · 2015Article
- Mechanistic insights into elastin degradation by pseudolysin, the major virulence factor of the opportunistic pathogen Pseudomonas aeruginosa.Scientific reports · 2015Article
- Inflammation in intervertebral disc degeneration and regeneration.Journal of the Royal Society, Interface · 2015Review
Corrections and comments
- Comment onPeter C[corrected to Winlove C P]
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Elastic fibres have been revealed by both elastin immunostaining and conventional histological orcein-staining in the intervertebral discs of the bovine tail. These fibres are distributed in all regions of the disc but their organization varies from region to region. In the centre of the nucleus, long (> 150 microm) elastic fibres are orientated radially. In the transitional region between nucleus and annulus, the orientation of the elastic fibres changes, producing a criss-cross pattern. In the annulus itself, elastic fibres appear densely distributed in the region between the lamellae and also in 'bridges' across the lamellae, particularly in the adult. Elastic fibres are apparent within the lamellae, orientated parallel to the collagen fibres of each lamella, particularly in the young (12-day-old) discs. In the region between the disc and the cartilaginous endplate, elastic fibres appear to anchor into the plate and terminate there. The results of this study suggest that elastic fibres contribute to the mechanical functioning of the intervertebral disc. The varying organization of the elastic fibres in the different regions of the disc is likely to relate to the different regional loading patterns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.